HitPredict

Interactor 1: RHOU (Q7L0Q8)
Rho-related GTP-binding protein RhoU (CDC42-like GTPase 1) (GTP-binding protein-like 1) (Rho GTPase-like protein ARHU) (Ryu GTPase) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1)
Gene: RHOU

Interactor 2: DHCR7 (Q9UBM7)
7-dehydrocholesterol reductase (7-DHC reductase) (EC 1.3.1.21) (Cholesterol-5,6-epoxide hydrolase subunit DHCR7) (EC 3.3.2.11) (Delta7-sterol reductase) (Sterol Delta(7)-reductase) (Sterol reductase SR-2)
Gene: DHCR7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 258 Hs			1 475
+	Hs
		962593 RHOA_HUMAN (51-231): 1.74e-90: 267: 46.41		DHCR7_HUMAN (1-475): 0: 568: 100.00
+	Hs
		466509 RHOC_HUMAN (51-231): 6.88e-90: 265: 46.96		DHCR7_HUMAN (1-475): 0: 568: 100.00
+	Hs
		1396651 RHOV_HUMAN (49-258): 3.84e-87: 260: 60.66		DHCR7_HUMAN (1-475): 0: 568: 100.00
+	Hs
		1015877 RHOG_HUMAN (48-233): 3.07e-83: 249: 48.93		DHCR7_HUMAN (1-475): 0: 568: 100.00
+	Hs
		581353 RAC2_HUMAN (50-233): 1.62e-78: 236: 56.52		DHCR7_HUMAN (1-475): 0: 568: 100.00
+	Hs
		988789 RAC1_HUMAN (50-234): 2.46e-76: 231: 56.76		DHCR7_HUMAN (1-475): 0: 568: 100.00
+	Hs
		976633 RB11A_HUMAN (39-256): 1.44e-74: 227: 26.87		DHCR7_HUMAN (1-475): 0: 568: 100.00
+	Hs
		955714 CDC42_HUMAN (50-236): 2.23e-74: 226: 58.82		DHCR7_HUMAN (1-475): 0: 568: 100.00
+	Hs
		953733 RAC3_HUMAN (50-223): 1.44e-73: 224: 58.62		DHCR7_HUMAN (1-475): 0: 568: 100.00
+	Hs
		962054 RHOA_HUMAN (51-231): 1.74e-90: 267: 46.41		LBR_HUMAN (31-475): 0: 523: 33.56
+	Hs
		466255 RHOC_HUMAN (51-231): 6.88e-90: 265: 46.96		LBR_HUMAN (31-475): 0: 523: 33.56
+	Hs
		601479 RHOQ_HUMAN (50-221): 2.7e-66: 206: 56.40		DHCR7_HUMAN (1-475): 0: 568: 100.00
+	Hs
		1015443 RHOG_HUMAN (48-233): 3.07e-83: 249: 48.93		LBR_HUMAN (31-475): 0: 523: 33.56
+	Hs
		1433559 RHOJ_HUMAN (40-238): 2.65e-63: 199: 51.26		DHCR7_HUMAN (1-475): 0: 568: 100.00
+	Hs
		581054 RAC2_HUMAN (50-233): 1.62e-78: 236: 56.52		LBR_HUMAN (31-475): 0: 523: 33.56
+	Hs
		988371 RAC1_HUMAN (50-234): 2.46e-76: 231: 56.76		LBR_HUMAN (31-475): 0: 523: 33.56
+	Hs
		955178 CDC42_HUMAN (50-236): 2.23e-74: 226: 58.82		LBR_HUMAN (31-475): 0: 523: 33.56
+	Hs
		953453 RAC3_HUMAN (50-223): 1.44e-73: 224: 58.62		LBR_HUMAN (31-475): 0: 523: 33.56
+	Hs
		1131827 RHOJ_HUMAN (40-238): 2.65e-63: 199: 51.26		LBR_HUMAN (31-475): 0: 523: 33.56