HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: LRCH1 (Q9Y2L9)
Leucine-rich repeat and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81)
Gene: LRCH1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LRR_8~Ras
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 728
+	Hs
		988387 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		RSU1_HUMAN (60-322): 1.44e-54: 190: 29.21
+	Hs
		601286 RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94		SCRIB_HUMAN (16-222): 4.3e-30: 129: 21.70
+	Hs
		601412 RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94		ERBIN_HUMAN (43-199): 3.28e-26: 117: 22.79
+	Hs
		1122344 RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17		SCRIB_HUMAN (16-222): 4.3e-30: 129: 21.70
+	Hs
		988360 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		SCRIB_HUMAN (16-222): 4.3e-30: 129: 21.70
+	Hs
		1401933 RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17		ERBIN_HUMAN (43-199): 3.28e-26: 117: 22.79
+	Hs
		601364 RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94		LRC8A_HUMAN (63-184): 5.97e-22: 103: 25.60
+	Hs
		1015432 RHOG_HUMAN (1-191): 7.33e-80: 237: 60.73		SCRIB_HUMAN (16-222): 4.3e-30: 129: 21.70
+	Hs
		955158 CDC42_HUMAN (1-191): 9.95e-80: 237: 100.00		SCRIB_HUMAN (16-222): 4.3e-30: 129: 21.70
+	Hs
		601384 RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94		LRC8C_HUMAN (69-310): 2.02e-19: 95.2: 20.94
+	Hs
		988630 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		ERBIN_HUMAN (43-199): 3.28e-26: 117: 22.79
+	Hs
		1310840 RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17		LRC8A_HUMAN (63-184): 5.97e-22: 103: 25.60
+	Hs
		1015697 RHOG_HUMAN (1-191): 7.33e-80: 237: 60.73		ERBIN_HUMAN (43-199): 3.28e-26: 117: 22.79
+	Hs
		955500 CDC42_HUMAN (1-191): 9.95e-80: 237: 100.00		ERBIN_HUMAN (43-199): 3.28e-26: 117: 22.79
+	Hs
		988509 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		LRC8A_HUMAN (63-184): 5.97e-22: 103: 25.60
+	Hs
		1015583 RHOG_HUMAN (1-191): 7.33e-80: 237: 60.73		LRC8A_HUMAN (63-184): 5.97e-22: 103: 25.60
+	Hs
		955358 CDC42_HUMAN (1-191): 9.95e-80: 237: 100.00		LRC8A_HUMAN (63-184): 5.97e-22: 103: 25.60
+	Hs
		955280 CDC42_HUMAN (1-191): 9.95e-80: 237: 100.00		LRCH2_HUMAN (3-165): 3.52e-19: 94.4: 13.94
+	Hs
		988609 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		LRCH3_HUMAN (12-155): 1.88e-12: 72.8: 14.29
+	Hs
		955475 CDC42_HUMAN (1-191): 9.95e-80: 237: 100.00		LRCH3_HUMAN (12-155): 1.88e-12: 72.8: 14.29