HitPredict

Interactor 1: DAB1 (P97318)
Disabled homolog 1
Gene: DAB1

Interactor 2: CRK (Q64010)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	15062102, 15316068
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001764 - neuron migration GO:0005737 - cytoplasm GO:0016358 - dendrite development GO:0021766 - hippocampus development GO:0042169 - SH2 domain binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 588 Mm			1 304
+	Hs
		269124 DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50		CRK_HUMAN (1-304): 1.22e-69: 220: 99.67
+	Mm
		815088 DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00		CRKL_MOUSE (2-302): 6.66e-60: 195: 47.42
+	Hs
		269125 DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50		CRKL_HUMAN (2-302): 3.72e-60: 195: 48.39
+	Mm
		956228 DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00		PLCG1_MOUSE (2-294): 7.92e-28: 115: 16.98
+	Mm
		223010 DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00		NCK2_MOUSE (2-117): 1.29e-15: 78.4: 24.79
+	Mm
		956235 DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00		NCK1_MOUSE (2-99): 2.47e-13: 71.7: 18.18
+	Hs
		208964 DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50		NCK2_HUMAN (2-117): 8.52e-14: 73.2: 22.22
+	Hs
		269120 DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50		NCK1_HUMAN (2-99): 2.87e-13: 71.4: 18.18
+	Hs
		269176 DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50		SH3K1_HUMAN (114-193): 4.42e-11: 65.2: 21.95
+	Hs
		269148 DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50		ITSN1_HUMAN (207-302): 2.54e-10: 63.3: 14.56
+	Dm
		957161 DAB_DROME (2-583): 9.69e-46: 176: 17.93		GRAP_DROME (135-293): 2.55e-24: 99.5: 18.18
+	Rn
		924995 SHC1_RAT (8-354): 9.65e-46: 169: 12.53		GRB2_RAT (135-297): 3.88e-26: 104: 15.67
+	Mm
		957139 DAB2_MOUSE (8-587): 2.89e-40: 158: 25.71		GRB2_MOUSE (135-297): 2.89e-26: 104: 15.67
+	Ce
		283752 CED6_CAEEL (5-482): 3.11e-42: 160: 14.58		VAV_CAEEL (13-194): 4.54e-22: 98.4: 23.94
+	Hs
		1191815 ANS1B_HUMAN (8-229): 3.86e-44: 171: 16.81		CD2AP_HUMAN (1-186): 3.46e-14: 74.8: 17.45
+	Dm
		112569 NUMB_DROME (16-521): 7.19e-45: 169: 13.48		M9ND00_DROME (39-259): 1.76e-14: 76: 14.29
+	Hs
		209098 ANS1B_HUMAN (8-229): 3.86e-44: 171: 16.81		NCK2_HUMAN (2-117): 8.52e-14: 73.2: 22.22
+	Mm
		1206702 ANS1B_MOUSE (8-213): 6.78e-42: 164: 17.06		ITSN1_MOUSE (150-302): 8.46e-12: 67.9: 15.06
+	Hs
		1115812 Q49AR9_HUMAN (11-321): 2.68e-43: 164: 15.87		SH3K1_HUMAN (114-193): 4.42e-11: 65.2: 21.95
+	Ce
		283754 CED6_CAEEL (5-482): 3.11e-42: 160: 14.58		Q9U2T9_CAEEL (138-292): 5.55e-10: 62.2: 20.46