HitPredict

Interactor 1: NRP1 (P97333)
Neuropilin-1 (A5 protein) (CD antigen CD304)
Gene: NRP1

Interactor 2: SEM6D (Q76KF0)
Semaphorin-6D
Gene: Sema6d

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	26633812
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	CUB~Sema
Common GO terms	GO:0001755 - neural crest cell migration GO:0005886 - plasma membrane GO:0007411 - axon guidance GO:0048843 - negative regulation of axon extension involved in axon guidance GO:0071526 - semaphorin-plexin signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 923 Mm			1 1073
+	Mm
		192796 NRP1_MOUSE (1-923): 0: 1085: 100.00		SEM6A_MOUSE (17-1067): 0: 1107: 45.20
+	Mm
		139667 NRP1_MOUSE (1-923): 0: 1085: 100.00		SEM3A_MOUSE (1-622): 0: 657: 30.60
+	Hs
		155353 NRP1_HUMAN (1-923): 0: 1064: 93.17		SEM3A_HUMAN (1-627): 0: 663: 31.03
+	Mm
		956250 NRP1_MOUSE (1-923): 0: 1085: 100.00		SEM3D_MOUSE (2-628): 0: 641: 31.74
+	Mm
		956241 NRP1_MOUSE (1-923): 0: 1085: 100.00		Q0VGP2_MOUSE (6-625): 0: 627: 28.95
+	Mm
		936363 NRP1_MOUSE (1-923): 0: 1085: 100.00		SEM3E_MOUSE (13-628): 0: 626: 28.48
+	Mm
		956246 NRP1_MOUSE (1-923): 0: 1085: 100.00		SEM3C_MOUSE (1-625): 0: 618: 28.28
+	Mm
		956255 NRP1_MOUSE (1-923): 0: 1085: 100.00		SEM6C_MOUSE (19-814): 0: 583: 42.66
+	Mm
		292032 NRP1_MOUSE (1-923): 0: 1085: 100.00		SEM3F_MOUSE (4-616): 0: 578: 28.05
+	Mm
		956247 NRP1_MOUSE (1-923): 0: 1085: 100.00		SEM4C_MOUSE (1-609): 0: 561: 28.07
+	Mm
		140339 NRP1_MOUSE (1-923): 0: 1085: 100.00		SEM4D_MOUSE (11-611): 1.24e-179: 548: 31.46
+	Mm
		956257 NRP1_MOUSE (1-923): 0: 1085: 100.00		SEM4F_MOUSE (15-632): 6.34e-173: 527: 26.66
+	Mm
		956245 NRP1_MOUSE (1-923): 0: 1085: 100.00		SEM4B_MOUSE (49-629): 1.68e-170: 523: 27.61
+	Mm
		139663 NRP2_MOUSE (5-923): 0: 898: 44.10		SEM3A_MOUSE (1-622): 0: 657: 30.60
+	Mm
		192664 NRP2_MOUSE (5-923): 0: 898: 44.10		Q0VGP2_MOUSE (6-625): 0: 627: 28.95
+	Mm
		192663 NRP2_MOUSE (5-923): 0: 898: 44.10		SEM3E_MOUSE (13-628): 0: 626: 28.48
+	Hs
		234430 NRP2_HUMAN (5-923): 0: 913: 44.14		SEM3F_HUMAN (4-616): 0: 574: 28.51
+	Mm
		192660 NRP2_MOUSE (5-923): 0: 898: 44.10		SEM3F_MOUSE (4-616): 0: 578: 28.05
+	Mm
		192666 NRP2_MOUSE (5-923): 0: 898: 44.10		SEM3G_MOUSE (2-622): 0: 572: 27.98
+	Mm
		192667 NRP2_MOUSE (5-923): 0: 898: 44.10		SEM4B_MOUSE (49-629): 1.68e-170: 523: 27.61