Interactor 1: FOXH1 (O75593)
Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast-1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2)
Gene: FOXH1

Interactor 2: ZIC1 (Q15915)
Zinc finger protein ZIC 1 (Zinc finger protein 201) (Zinc finger protein of the cerebellum 1)
Gene: ZIC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.61 0.60 0.606

The method score is based on:

Property Details
Experiments 32296183, unassigned1304
Identification Methods two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 365
Hs

1 447
+ Hs
+ Ce
+ Ce
+ Hs
+ Dm
+ Dm
+ Dm
+ Hs

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Last updated: 15 Jul 2024