Interactor 1: EYA1 (P97767)
Eyes absent homolog 1 (EC 3.1.3.16) (EC 3.1.3.48)
Gene: EYA1

Interactor 2: SIX4 (Q61321)
Homeobox protein SIX4 (Sine oculis homeobox homolog 4) (Skeletal muscle-specific ARE-binding protein AREC3)
Gene: SIX4

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.46 1.00 0.680

The method score is based on:

Property Details
Experiments 11950062
Identification Methods two hybrid, pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Hydrolase~SIX1_SD
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0042472 - inner ear morphogenesis
GO:0045893 - positive regulation of DNA-templated transcription
GO:0045944 - positive regulation of transcription by RNA polymerase II
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 591
Mm

1 775
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024