HitPredict

Interactor 1: DAB2 (P98078)
Disabled homolog 2 (Adaptor molecule disabled-2) (Differentially expressed in ovarian carcinoma 2) (DOC-2) (Mitogen-responsive phosphoprotein)
Gene: DAB2

Interactor 2: EP15R (Q60902)
Epidermal growth factor receptor substrate 15-like 1 (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs) (Eps15-related protein) (Eps15R)
Gene: Eps15l1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	22648170
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0030132 - clathrin coat of coated pit
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 766 Mm			1 907
+	Hs
		787894 DAB2_HUMAN (1-766): 8.87e-80: 273: 81.76		EPS15_HUMAN (1-905): 5.4e-124: 398: 41.68
+	Mm
		787999 DAB2_MOUSE (1-766): 9.01e-96: 316: 100.00		EPS15_MOUSE (1-905): 3.61e-107: 353: 42.86
+	Hs
		833668 NUMB_HUMAN (26-678): 6e-47: 179: 14.24		EP15R_HUMAN (1-860): 2.72e-148: 461: 92.23
+	Mm
		1141842 ANS1B_MOUSE (2-231): 5.14e-41: 164: 17.95		EP15R_MOUSE (1-907): 2.44e-145: 455: 100.00
+	Hs
		787868 NUMB_HUMAN (26-678): 6e-47: 179: 14.24		EPS15_HUMAN (1-905): 5.4e-124: 398: 41.68
+	Mm
		788008 NUMB_MOUSE (26-678): 7.52e-45: 173: 13.19		EPS15_MOUSE (1-905): 3.61e-107: 353: 42.86
+	Mm
		957157 DAB2_MOUSE (1-766): 9.01e-96: 316: 100.00		ITSN1_MOUSE (2-524): 3.68e-35: 147: 14.70
+	Hs
		957186 DAB2_HUMAN (1-766): 8.87e-80: 273: 81.76		ITSN1_HUMAN (2-522): 3.16e-37: 154: 13.52
+	Hs
		957209 DAB2_HUMAN (1-766): 8.87e-80: 273: 81.76		REPS1_HUMAN (9-127): 1.01e-18: 93.6: 22.69
+	Mm
		1206702 ANS1B_MOUSE (2-231): 5.14e-41: 164: 17.95		ITSN1_MOUSE (2-524): 3.68e-35: 147: 14.70
+	Hs
		269148 DAB1_HUMAN (11-617): 1.62e-37: 150: 23.57		ITSN1_HUMAN (2-522): 3.16e-37: 154: 13.52
+	Dm
		112569 NUMB_DROME (24-531): 1.64e-38: 153: 11.91		M9ND00_DROME (1-465): 4.54e-32: 137: 10.71
+	Hs
		833640 NUMB_HUMAN (26-678): 6e-47: 179: 14.24		REPS1_HUMAN (9-127): 1.01e-18: 93.6: 22.69
+	Ce
		60778 A5JYR4_CAEEL (5-289): 9.7e-38: 149: 28.91		Q8WSP1_CAEEL (114-214): 6.41e-20: 97.1: 53.47
+	Dm
		561284 NUMB_DROME (24-531): 1.64e-38: 153: 11.91		Q8T8W3_DROME (126-214): 1.05e-18: 92.8: 51.69
+	Dm
		91154 NUMB_DROME (24-531): 1.64e-38: 153: 11.91		E3CTP7_DROME (467-658): 1.4e-16: 86.6: 10.55
+	Ce
		60780 A5JYR4_CAEEL (5-289): 9.7e-38: 149: 28.91		Q9U2T9_CAEEL (374-787): 1.3e-11: 70.8: 11.93
+	Ce
		1353620 NUMB1_CAEEL (24-429): 3.32e-35: 143: 12.59		Q9U2T9_CAEEL (374-787): 1.3e-11: 70.8: 11.93
+	Ce
		283754 CED6_CAEEL (1-410): 3.55e-35: 142: 16.24		Q9U2T9_CAEEL (374-787): 1.3e-11: 70.8: 11.93