HitPredict

Interactor 1: LRP2 (P98164)
Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)
Gene: LRP2

Interactor 2: MAGI1 (Q96QZ7)
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (Atrophin-1-interacting protein 3) (AIP-3) (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Trinucleotide repeat-containing gene 19 protein) (WW domain-containing protein 3) (WWP3)
Gene: MAGI1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	11274227
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 4655 Hs			1 1491
+	Hs
		957608 LRP2_HUMAN (1-4655): 0: 3803: 100.00		DLG2_HUMAN (14-658): 7.28e-18: 92.2: 10.70
+	Hs
		942324 LRP2_HUMAN (1-4655): 0: 3803: 100.00		DLG4_HUMAN (14-112): 3.09e-17: 89.9: 19.23
+	Hs
		957631 LRP2_HUMAN (1-4655): 0: 3803: 100.00		DLG3_HUMAN (16-556): 6.49e-16: 85.6: 12.05
+	Mm
		57555 LRP2_MOUSE (22-4655): 0: 3723: 76.66		DLG4_MOUSE (14-110): 4.36e-17: 89.1: 19.61
+	Hs
		942339 LRP8_HUMAN (3464-3669): 8.96e-14: 80.7: 21.92		DLG4_HUMAN (14-112): 3.09e-17: 89.9: 19.23
+	Mm
		1143476 LRP8_MOUSE (2623-2869): 2.33e-11: 72.6: 16.36		DLG4_MOUSE (14-110): 4.36e-17: 89.1: 19.61
+	Mm
		69882 B1AXJ3_MOUSE (3424-3628): 4.43e-11: 71.8: 12.50		DLG4_MOUSE (14-110): 4.36e-17: 89.1: 19.61
+	Hs
		942331 LRP1_HUMAN (1102-1387): 4.45e-09: 65.6: 13.59		DLG4_HUMAN (14-112): 3.09e-17: 89.9: 19.23
+	Mm
		1143471 LRP1_MOUSE (3672-3974): 3.08e-09: 66: 10.16		DLG4_MOUSE (14-110): 4.36e-17: 89.1: 19.61