HitPredict

Interactor 1: RAB14 (P61106)
Ras-related protein Rab-14 (EC 3.6.5.2)
Gene: RAB14

Interactor 2: RB33B (Q9H082)
Ras-related protein Rab-33B (EC 3.6.5.2)
Gene: RAB33B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	31839598, 40437099
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0000139 - Golgi membrane GO:0003924 - GTPase activity GO:0003925 - G protein activity GO:0005525 - GTP binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 215 Hs			1 229
+	Hs
		956421 RAB2A_HUMAN (8-195): 2.15e-98: 286: 62.77		RAB2B_HUMAN (30-226): 7.59e-87: 257: 38.69
+	Mm
		925770 RAB2B_MOUSE (7-214): 6.01e-97: 282: 55.35		RAB2A_MOUSE (29-220): 8.35e-87: 257: 39.18
+	Hs
		956239 RAB2A_HUMAN (8-195): 2.15e-98: 286: 62.77		RAB1A_HUMAN (24-229): 3.77e-85: 253: 37.80
+	Hs
		956483 RAB2A_HUMAN (8-195): 2.15e-98: 286: 62.77		RAB1B_HUMAN (26-228): 8.02e-84: 249: 37.86
+	Hs
		956433 RAB2A_HUMAN (8-195): 2.15e-98: 286: 62.77		RAB1C_HUMAN (26-228): 3.35e-81: 242: 37.38
+	Hs
		630963 RAB4A_HUMAN (8-215): 1.05e-87: 259: 60.77		RB33B_HUMAN (1-229): 2.63e-89: 264: 100.00
+	Hs
		956434 RAB2A_HUMAN (8-195): 2.15e-98: 286: 62.77		RAB8B_HUMAN (26-226): 2.36e-78: 235: 35.61
+	Hs
		956233 RAB14_HUMAN (1-215): 4.71e-88: 260: 100.00		RAB2A_HUMAN (29-220): 8.35e-87: 257: 39.18
+	Hs
		957980 RAB14_HUMAN (1-215): 4.71e-88: 260: 100.00		RAB2B_HUMAN (30-226): 7.59e-87: 257: 38.69
+	Hs
		630747 RAB4A_HUMAN (8-215): 1.05e-87: 259: 60.77		RAB2A_HUMAN (29-220): 8.35e-87: 257: 39.18
+	Hs
		630906 RAB4A_HUMAN (8-215): 1.05e-87: 259: 60.77		RAB2B_HUMAN (30-226): 7.59e-87: 257: 38.69
+	Hs
		957907 RAB14_HUMAN (1-215): 4.71e-88: 260: 100.00		RAB1A_HUMAN (24-229): 3.77e-85: 253: 37.80
+	Hs
		630754 RAB4A_HUMAN (8-215): 1.05e-87: 259: 60.77		RAB1A_HUMAN (24-229): 3.77e-85: 253: 37.80
+	Hs
		958022 RAB14_HUMAN (1-215): 4.71e-88: 260: 100.00		RAB1B_HUMAN (26-228): 8.02e-84: 249: 37.86
+	Mm
		940538 RAB4A_MOUSE (8-215): 1.95e-87: 258: 60.29		RAB1B_MOUSE (26-228): 9.66e-84: 249: 37.86
+	Mm
		981416 RAB1A_MOUSE (1-215): 9.99e-87: 256: 41.86		RAB1B_MOUSE (26-228): 9.66e-84: 249: 37.86
+	Hs
		955904 RAB14_HUMAN (1-215): 4.71e-88: 260: 100.00		RAB8A_HUMAN (26-226): 1.89e-78: 236: 37.56
+	Hs
		956703 RAB14_HUMAN (1-215): 4.71e-88: 260: 100.00		RAB10_HUMAN (26-229): 1.49e-78: 236: 35.78
+	Hs
		957988 RAB14_HUMAN (1-215): 4.71e-88: 260: 100.00		RAB8B_HUMAN (26-226): 2.36e-78: 235: 35.61
+	Mm
		981423 RAB1A_MOUSE (1-215): 9.99e-87: 256: 41.86		RAB37_MOUSE (5-228): 8.74e-79: 237: 32.89