HitPredict - High confidence protein-protein interactions

Interactor 1: ARP2 (P61160)
Actin-related protein 2 (Actin-like protein 2)
Gene: ACTR2

Interactor 2: ARP2 (P61160)
Actin-related protein 2 (Actin-like protein 2)
Gene: ACTR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	29568061
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~Actin
Common GO terms	GO:0003779 - actin binding GO:0005200 - structural constituent of cytoskeleton GO:0005524 - ATP binding GO:0005576 - extracellular region GO:0005634 - nucleus and 25 others more... GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005885 - Arp2/3 protein complex GO:0005925 - focal adhesion GO:0005938 - cell cortex GO:0007163 - establishment or maintenance of cell polarity GO:0008356 - asymmetric cell division GO:0010592 - positive regulation of lamellipodium assembly GO:0015629 - actin cytoskeleton GO:0016020 - membrane GO:0016344 - meiotic chromosome movement towards spindle pole GO:0016482 - cytosolic transport GO:0030478 - actin cap GO:0033206 - meiotic cytokinesis GO:0034314 - Arp2/3 complex-mediated actin nucleation GO:0035578 - azurophil granule lumen GO:0035861 - site of double-strand break GO:0042995 - cell projection GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0051653 - spindle localization GO:0060271 - cilium assembly GO:0070062 - extracellular exosome GO:0071346 - cellular response to type II interferon GO:1904813 - ficolin-1-rich granule lumen GO:1905168 - positive regulation of double-strand break repair via homologous recombination
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1	394
Hs

1	394

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Last updated: 11Aug2025