HitPredict

Interactor 1: CSN2 (P61201)
COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)
Gene: COPS2

Interactor 2: DDB2 (Q92466)
DNA damage-binding protein 2 (DDB p48 subunit) (DDBb) (Damage-specific DNA-binding protein 2) (UV-damaged DNA-binding protein 2) (UV-DDB 2)
Gene: DDB2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.742

Property	Details
Experiments	26186194, 28514442, 33961781, 12732143, 16260596, 19295130, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 443 Hs			1 427
+	Hs
		958629 CSN2_HUMAN (1-443): 3.16e-127: 377: 100.00		ERCC8_HUMAN (114-324): 1.49e-59: 201: 23.21
+	Hs
		1094387 CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02		DDB2_HUMAN (1-427): 3.18e-95: 294: 100.00
+	Hs
		91673 C9JFE4_HUMAN (17-443): 1.42e-78: 253: 14.93		DDB2_HUMAN (1-427): 3.18e-95: 294: 100.00
+	Hs
		1363082 CSN4_HUMAN (54-440): 8.18e-74: 238: 16.25		DDB2_HUMAN (1-427): 3.18e-95: 294: 100.00
+	Hs
		128034 PSD11_HUMAN (35-442): 5.46e-89: 278: 22.43		FBXW7_HUMAN (8-311): 5.97e-65: 222: 11.94
+	Hs
		1094322 CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02		ERCC8_HUMAN (114-324): 1.49e-59: 201: 23.21
+	Hs
		127922 PSD11_HUMAN (35-442): 5.46e-89: 278: 22.43		WDR5_HUMAN (236-427): 6.67e-50: 173: 21.76
+	Hs
		1098371 CSN4_HUMAN (54-440): 8.18e-74: 238: 16.25		ERCC8_HUMAN (114-324): 1.49e-59: 201: 23.21
+	Hs
		128195 PSD12_HUMAN (39-440): 8.73e-83: 263: 12.80		WDR5_HUMAN (236-427): 6.67e-50: 173: 21.76