HitPredict

Interactor 1: MAX (P61244)
Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X)
Gene: MAX

Interactor 2: MAX (P61244)
Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X)
Gene: MAX

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.959

The method score is based on:

Property Details
Experiments 9050988, 12553908, 9115440, 31839598, 17217336, 20946988, 25609649, 9184233
Identification Methods pull down, x-ray crystallography, cross-linking study, affinity chromatography technology, tandem affinity purification, two hybrid
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HLH~HLH
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003677 - DNA binding
and 16 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 160
Hs

1 160
+ Hs
+ At
+ Mm
+ At
+ Hs
+ Hs
+ Hs
+ Gg
+ Rn
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
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+ Mm
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+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025