HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: L2GL1 (Q15334)
Lethal(2) giant larvae protein homolog 1 (LLGL) (DLG4) (Hugl-1) (Human homolog to the D-lgl gene protein)
Gene: LLGL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005856 - cytoskeleton GO:0005886 - plasma membrane GO:0019901 - protein kinase binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 1064
+	Hs
		988384 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		466266 RHOC_HUMAN (1-193): 1.75e-77: 231: 91.71		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		1015453 RHOG_HUMAN (1-193): 1.49e-76: 229: 54.40		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		955193 CDC42_HUMAN (1-193): 4.17e-76: 228: 52.33		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		581064 RAC2_HUMAN (1-193): 2.82e-75: 226: 53.61		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		953463 RAC3_HUMAN (1-179): 3.87e-73: 220: 57.54		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		978023 RHOB_HUMAN (1-191): 9.8e-73: 219: 83.94		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		126610 RHOD_HUMAN (7-182): 1.69e-69: 212: 53.98		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		988452 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		L2GL2_HUMAN (5-979): 0: 1216: 56.97
+	Hs
		962141 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		STXB5_HUMAN (14-1064): 0: 1055: 25.47
+	Hs
		988430 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		STXB5_HUMAN (14-1064): 0: 1055: 25.47
+	Hs
		1015504 RHOG_HUMAN (1-193): 1.49e-76: 229: 54.40		STXB5_HUMAN (14-1064): 0: 1055: 25.47