HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: INADL (Q8NI35)
InaD-like protein (Inadl protein) (hINADL) (Channel-interacting PDZ domain-containing protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions)
Gene: PATJ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030054 - cell junction GO:0043296 - apical junction complex GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1801
+	Hs
		961996 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		PTN13_HUMAN (1500-1798): 6.7e-24: 112: 16.78
+	Hs
		988322 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		PTN13_HUMAN (1500-1798): 6.7e-24: 112: 16.78
+	Hs
		961999 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		DLG1_HUMAN (546-984): 8.08e-23: 108: 16.63
+	Hs
		466227 RHOC_HUMAN (1-193): 1.75e-77: 231: 91.71		PTN13_HUMAN (1500-1798): 6.7e-24: 112: 16.78
+	Hs
		988325 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		DLG1_HUMAN (546-984): 8.08e-23: 108: 16.63
+	Hs
		955103 CDC42_HUMAN (1-193): 4.17e-76: 228: 52.33		PTN13_HUMAN (1500-1798): 6.7e-24: 112: 16.78
+	Hs
		466228 RHOC_HUMAN (1-193): 1.75e-77: 231: 91.71		DLG1_HUMAN (546-984): 8.08e-23: 108: 16.63
+	Hs
		1015397 RHOG_HUMAN (1-193): 1.49e-76: 229: 54.40		DLG1_HUMAN (546-984): 8.08e-23: 108: 16.63
+	Hs
		962343 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		DLG3_HUMAN (1419-1666): 2.49e-20: 100: 23.15
+	Hs
		955106 CDC42_HUMAN (1-193): 4.17e-76: 228: 52.33		DLG1_HUMAN (546-984): 8.08e-23: 108: 16.63
+	Hs
		962401 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		MAGI1_HUMAN (1-292): 1.74e-19: 98.2: 18.15
+	Hs
		988627 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		MAGI1_HUMAN (1-292): 1.74e-19: 98.2: 18.15
+	Hs
		1015652 RHOG_HUMAN (1-193): 1.49e-76: 229: 54.40		DLG3_HUMAN (1419-1666): 2.49e-20: 100: 23.15
+	Mm
		988891 RAC1_MOUSE (1-193): 7e-79: 235: 57.22		DLG4_MOUSE (636-947): 3.24e-16: 86.7: 14.38
+	Hs
		466372 RHOC_HUMAN (1-193): 1.75e-77: 231: 91.71		LNX1_HUMAN (1620-1796): 3.54e-14: 80: 19.21
+	Hs
		962039 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		SCRIB_HUMAN (142-438): 1.39e-10: 68.9: 26.78
+	Hs
		988360 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		SCRIB_HUMAN (142-438): 1.39e-10: 68.9: 26.78
+	Hs
		466247 RHOC_HUMAN (1-193): 1.75e-77: 231: 91.71		SCRIB_HUMAN (142-438): 1.39e-10: 68.9: 26.78
+	Hs
		1015432 RHOG_HUMAN (1-193): 1.49e-76: 229: 54.40		SCRIB_HUMAN (142-438): 1.39e-10: 68.9: 26.78
+	Hs
		955158 CDC42_HUMAN (1-193): 4.17e-76: 228: 52.33		SCRIB_HUMAN (142-438): 1.39e-10: 68.9: 26.78