Interactor 1: MDM2 (Q00987)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Hdm2) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)
Gene: MDM2

Interactor 2: UBE4A (Q14139)
Ubiquitin conjugation factor E4 A (EC 2.3.2.27) (RING-type E3 ubiquitin transferase E4 A)
Gene: UBE4A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 35136024
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000209 - protein polyubiquitination
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 491
Hs

1 1066
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024