HitPredict

Interactor 1: SPTB2 (Q01082)
Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)
Gene: SPTBN1

Interactor 2: TP4A2 (Q12974)
Protein tyrosine phosphatase type IVA 2 (EC 3.1.3.48) (HU-PP-1) (OV-1) (PTP(CAAXII)) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2)
Gene: PTP4A2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	27880917
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 2364 Hs			1 167
+	Hs
		890611 SPTB2_HUMAN (1-2364): 0: 751: 100.00		PTEN_HUMAN (2-158): 1.56e-47: 160: 19.67
+	Dm
		527096 SPTCA_DROME (288-1964): 1.34e-160: 555: 18.16		Q7KMQ6_DROME (2-149): 4.26e-47: 161: 20.61
+	Hs
		360634 SPTA1_HUMAN (179-1394): 3.14e-92: 337: 19.60		PTEN_HUMAN (2-158): 1.56e-47: 160: 19.67
+	Dm
		1181075 Q7KV70_DROME (213-2065): 9.57e-54: 211: 16.61		Q7KMQ6_DROME (2-149): 4.26e-47: 161: 20.61
+	Mm
		82741 B9EKJ1_MOUSE (266-1626): 1.35e-50: 201: 19.03		PTEN_MOUSE (2-158): 1.51e-47: 160: 19.67
+	Hs
		1021793 SPTN1_HUMAN (152-1087): 9.93e-19: 96.3: 16.89		TP4A2_HUMAN (1-167): 6.88e-68: 205: 100.00
+	Hs
		513897 DMD_HUMAN (234-2093): 2.37e-21: 105: 9.67		TENS1_HUMAN (1-162): 1.57e-50: 175: 16.20
+	Hs
		809178 UTRN_HUMAN (212-2073): 1e-17: 93.2: 10.02		TENS1_HUMAN (1-162): 1.57e-50: 175: 16.20
+	Hs
		513870 DMD_HUMAN (234-2093): 2.37e-21: 105: 9.67		TENS2_HUMAN (1-149): 9.18e-45: 158: 13.86
+	Hs
		513871 DMD_HUMAN (234-2093): 2.37e-21: 105: 9.67		TENS3_HUMAN (1-148): 3.46e-44: 157: 13.33
+	Hs
		161655 SPTN1_HUMAN (152-1087): 9.93e-19: 96.3: 16.89		GAK_HUMAN (6-151): 5.31e-46: 162: 17.09
+	Hs
		890656 SPTN1_HUMAN (152-1087): 9.93e-19: 96.3: 16.89		PTEN_HUMAN (2-158): 1.56e-47: 160: 19.67
+	Hs
		809090 UTRN_HUMAN (212-2073): 1e-17: 93.2: 10.02		PTEN_HUMAN (2-158): 1.56e-47: 160: 19.67
+	Hs
		809129 UTRN_HUMAN (212-2073): 1e-17: 93.2: 10.02		TENS2_HUMAN (1-149): 9.18e-45: 158: 13.86
+	Hs
		809130 UTRN_HUMAN (212-2073): 1e-17: 93.2: 10.02		TENS3_HUMAN (1-148): 3.46e-44: 157: 13.33
+	Hs
		890672 PLEC_HUMAN (222-1144): 1.08e-16: 89.7: 11.59		PTEN_HUMAN (2-158): 1.56e-47: 160: 19.67