Protein: DCAF5
DDB1- and CUL4-associated factor 5 (Breakpoint cluster region protein 2) (BCRP2) (WD repeat-containing protein 22)

Gene: DCAF5
Organism: Homo sapiens
Interactions: 99
UniProt ID: Q96JK2

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0016567 - protein ubiquitination
GO:0045717 - negative regulation of fatty acid biosynthetic process
GO:0080008 - Cul4-RING E3 ubiquitin ligase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1395137

TCPH
T-complex protein 1 subunit eta

4

20

High-throughput

0.892

High

1157870

DDB1
DNA damage-binding protein 1

4

20

Small-scale

0.890

High

532873

CH60
60 kDa heat shock protein, mitochondrial

3

12

High-throughput

0.861

High

821508

TCPZ
T-complex protein 1 subunit zeta

3

20

High-throughput

0.861

High

882093

TCPG
T-complex protein 1 subunit gamma

4

20

High-throughput

0.797

High

1007205

TCPB
T-complex protein 1 subunit beta

4

20

High-throughput

0.797

High

1395141

DDA1
DET1- and DDB1-associated protein 1

2

5

High-throughput

0.789

High

610830

TCPA
T-complex protein 1 subunit alpha

3

20

High-throughput

0.770

High

1363673

TCPW
T-complex protein 1 subunit zeta-2

3

20

High-throughput

0.770

High

876119

TCPE
T-complex protein 1 subunit epsilon

3

20

High-throughput

0.765

High

943685

RWD2B
RWD domain-containing protein 2B

3

0

High-throughput

0.720

High

899176

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.691

High

899529

TCPD
T-complex protein 1 subunit delta

1

20

High-throughput

0.691

High

1099757

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

2

High-throughput

0.691

High

1395143

PDCL3
Phosducin-like protein 3

1

5

High-throughput

0.691

High

1395150

DCA13
DDB1- and CUL4-associated factor 13

1

18

High-throughput

0.691

High

1115000

CUL4A
Cullin-4A

4

20

Small-scale

0.686

High

182174

PFD6
Prefoldin subunit 6

3

7

High-throughput

0.667

High

963353

PFD3
Prefoldin subunit 3

3

8

High-throughput

0.667

High

1395147

PFD4
Prefoldin subunit 4

3

5

High-throughput

0.667

High

261855

PFD1
Prefoldin subunit 1

3

4

High-throughput

0.662

High

1115361

CUL4B
Cullin-4B

3

20

Small-scale

0.660

High

972521

RS14
Small ribosomal subunit protein uS11

2

8

High-throughput

0.628

High

1395146

E41L5
Band 4.1-like protein 5

2

7

High-throughput

0.628

High

711584

NK3R
Neuromedin-K receptor

1

2

High-throughput

0.618

High

194300

R113A
E3 ubiquitin-protein ligase RNF113A

1

2

High-throughput

0.618

High

762035

GRK5
G protein-coupled receptor kinase 5

1

10

High-throughput

0.618

High

1255090

TRI67
Tripartite motif-containing protein 67

1

17

High-throughput

0.618

High

1366118

DYRK2
Dual specificity tyrosine-phosphorylation-regulated kinase 2

2

18

Small-scale

0.611

High

1395135

PFD5
Prefoldin subunit 5

2

7

High-throughput

0.611

High

1395136

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

2

3

High-throughput

0.611

High

1012239

RT11
Small ribosomal subunit protein uS11m

3

8

High-throughput

0.609

High

882548

ARRB1
Beta-arrestin-1

2

0

High-throughput

0.602

High

1234705

TYW3
tRNA wybutosine-synthesizing protein 3 homolog

2

0

High-throughput

0.602

High

1395140

PYM1
Partner of Y14 and mago

2

0

High-throughput

0.602

High

685048

DNMT1
DNA

1

8

Small-scale

0.586

High

1395149

PDRG1
p53 and DNA damage-regulated protein 1

2

0

High-throughput

0.585

High

1395138

TCF25
Ribosome quality control complex subunit TCF25

2

1

High-throughput

0.574

High

1395139

SOST
Sclerostin

2

1

High-throughput

0.574

High

1395142

NUAK2
NUAK family SNF1-like kinase 2

2

9

High-throughput

0.574

High

1395145

GPBL1
Vasculin-like protein 1

2

2

High-throughput

0.574

High

848290

MAGA3
Melanoma-associated antigen 3

2

8

Small-scale

0.558

High

1395133

LMBL3
Lethal(3)malignant brain tumor-like protein 3

1

6

Small-scale

0.554

High

1115913

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

13

High-throughput

0.541

High

176861

DCLK1
Serine/threonine-protein kinase DCLK1

1

7

High-throughput

0.536

High

786217

LONM
Lon protease homolog, mitochondrial

1

13

High-throughput

0.536

High

1270322

SPT6H
Transcription elongation factor SPT6

1

5

High-throughput

0.536

High

1314962

ELOA2
Elongin-A2

1

6

High-throughput

0.536

High

1325074

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

2

High-throughput

0.536

High

1328514

RNF10
E3 ubiquitin-protein ligase RNF10

1

6

High-throughput

0.536

High

1370565

FGF11
Fibroblast growth factor 11

1

2

High-throughput

0.536

High

1370597

FGF14
Fibroblast growth factor 14

1

2

High-throughput

0.536

High

1395155

PFD2
Prefoldin subunit 2

1

5

High-throughput

0.536

High

1395158

RBMX2
RNA-binding motif protein, X-linked 2

1

14

High-throughput

0.536

High

1029137

E2F1
Transcription factor E2F1

1

4

Small-scale

0.515

High

1292073

SPA24
Spermatogenesis-associated protein 24

1

0

High-throughput

0.513

High

662636

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

4

High-throughput

0.500

High

221279

DCX
Neuronal migration protein doublecortin

1

4

High-throughput

0.489

High

252785

AP180
Clathrin coat assembly protein AP180

1

7

High-throughput

0.489

High

871178

TFPI2
Tissue factor pathway inhibitor 2

1

5

High-throughput

0.489

High

939904

DLX6
Homeobox protein DLX-6

1

3

High-throughput

0.489

High

1052900

HME1
Homeobox protein engrailed-1

1

1

High-throughput

0.489

High

1289080

GGN
Gametogenetin

1

14

High-throughput

0.489

High

1311015

SULF2
Extracellular sulfatase Sulf-2

1

1

High-throughput

0.489

High

1331839

SYT2
Synaptotagmin-2

1

3

High-throughput

0.489

High

1395156

ABT1
Activator of basal transcription 1

1

1

High-throughput

0.489

High

320753

UBXN7
UBX domain-containing protein 7

1

3

High-throughput

0.479

High

508449

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

12

High-throughput

0.479

High

872635

SOX2
Transcription factor SOX-2

1

17

Small-scale

0.479

High

1163754

PTN21
Tyrosine-protein phosphatase non-receptor type 21

1

14

High-throughput

0.479

High

1232376

SFRP4
Secreted frizzled-related protein 4

1

1

High-throughput

0.479

High

1289034

CATAC
Centrosomal AT-AC splicing factor

1

1

High-throughput

0.479

High

1357517

DCAF4
DDB1- and CUL4-associated factor 4

1

2

High-throughput

0.479

High

1370297

CSN5
COP9 signalosome complex subunit 5

1

13

High-throughput

0.479

High

1395144

SP110
Sp110 nuclear body protein

1

20

High-throughput

0.479

High

1395148

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

3

Small-scale

0.479

High

1395157

FZR1
Fizzy-related protein homolog

1

18

High-throughput

0.479

High

1395152

VAPA
Vesicle-associated membrane protein-associated protein A

1

2

High-throughput

0.470

High

279462

TULP3
Tubby-related protein 3

1

0

High-throughput

0.458

High

239172

ZNRD2
Protein ZNRD2

1

1

High-throughput

0.445

High

259051

DNJA2
DnaJ homolog subfamily A member 2

1

12

High-throughput

0.445

High

1218776

DC122
DDB1- and CUL4-associated factor 12-like protein 2

1

1

High-throughput

0.445

High

1272520

CSN6
COP9 signalosome complex subunit 6

1

8

High-throughput

0.445

High

1337909

ZNT7
Zinc transporter 7

1

1

High-throughput

0.445

High

106469

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

1178310

CL16A
Protein CLEC16A

1

1

High-throughput

0.437

High

1353010

SNX29
Sorting nexin-29

1

1

High-throughput

0.437

High

1395151

DJC28
DnaJ homolog subfamily C member 28

1

1

High-throughput

0.437

High

877710

SL9A3
Sodium/hydrogen exchanger 3

1

3

High-throughput

0.407

High

1288437

SO6A1
Solute carrier organic anion transporter family member 6A1

1

4

High-throughput

0.407

High

1395153

S53A1
Solute carrier family 53 member 1

1

1

High-throughput

0.407

High

1395154

SL9A2
Sodium/hydrogen exchanger 2

1

3

High-throughput

0.407

High

1081804

ZN816
Zinc finger protein 816

2

0

High-throughput

0.328

High

1187671

T10IP
Testis-specific protein 10-interacting protein

2

0

High-throughput

0.318

High

582110

PGAM2
Phosphoglycerate mutase 2

1

0

High-throughput

0.279

Low

1127459

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

1316048

TRM2A
tRNA

1

0

High-throughput

0.279

Low

1395134

CX058
Uncharacterized protein CXorf58

1

0

High-throughput

0.269

Low

1379931

LHX4
LIM/homeobox protein Lhx4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025