HitPredict

Interactor 1: SET (Q01105)
Protein SET (HLA-DR-associated protein II) (Inhibitor of granzyme A-activated DNase) (IGAAD) (PHAPII) (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template-activating factor I) (TAF-I)
Gene: SET

Interactor 2: H31T (Q16695)
Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)
Gene: H3-4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	11163245
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Histone~NAP
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 290 Hs			1 136
+	Hs
		934666 SET_HUMAN (1-236): 6.45e-89: 268: 100.00		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		952277 SET_HUMAN (1-236): 6.45e-89: 268: 100.00		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		934935 TSYL5_HUMAN (2-257): 3.11e-86: 265: 32.69		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		963844 SET_HUMAN (1-236): 6.45e-89: 268: 100.00		H32_HUMAN (1-136): 1.34e-60: 184: 96.32
+	Hs
		952444 TSYL5_HUMAN (2-257): 3.11e-86: 265: 32.69		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		1086346 TSYL4_HUMAN (31-235): 7.34e-85: 261: 36.59		H31T_HUMAN (1-136): 2.65e-61: 186: 100.00
+	Hs
		876755 NP1L1_HUMAN (2-278): 1.56e-83: 258: 18.13		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		876827 NP1L1_HUMAN (2-278): 1.56e-83: 258: 18.13		H32_HUMAN (1-136): 1.34e-60: 184: 96.32
+	Hs
		1086291 NP1L4_HUMAN (4-242): 5.86e-81: 250: 18.81		H31T_HUMAN (1-136): 2.65e-61: 186: 100.00
+	Hs
		1174639 NP1L4_HUMAN (4-242): 5.86e-81: 250: 18.81		H32_HUMAN (1-136): 1.34e-60: 184: 96.32
+	At
		886474 NAP1A_ARATH (18-239): 3.58e-72: 228: 22.55		H33_ARATH (1-136): 1.13e-61: 187: 93.38
+	At
		886475 NAP1B_ARATH (18-238): 2.68e-72: 228: 22.71		H33_ARATH (1-136): 1.13e-61: 187: 93.38
+	At
		886466 NAP1C_ARATH (18-239): 6.06e-71: 224: 22.99		H33_ARATH (1-136): 1.13e-61: 187: 93.38
+	At
		886671 NAP1A_ARATH (18-239): 3.58e-72: 228: 22.55		H31_ARATH (1-136): 3.02e-60: 183: 94.12
+	At
		886672 NAP1B_ARATH (18-238): 2.68e-72: 228: 22.71		H31_ARATH (1-136): 3.02e-60: 183: 94.12
+	At
		886665 NAP1C_ARATH (18-239): 6.06e-71: 224: 22.99		H31_ARATH (1-136): 3.02e-60: 183: 94.12
+	Dm
		356123 Q9W1G7_DROME (18-238): 1.82e-67: 216: 20.54		H3_DROME (1-136): 1.34e-60: 184: 96.32
+	Sc
		627669 NAP1_YEAST (6-286): 9.91e-70: 223: 20.45		H3_YEAST (1-136): 1.43e-55: 171: 86.03
+	Sc
		627600 NAP1_YEAST (6-286): 9.91e-70: 223: 20.45		CENPA_YEAST (18-134): 1.65e-41: 139: 53.33