HitPredict

Interactor 1: LMO4 (P61968)
LIM domain transcription factor LMO4 (Breast tumor autoantigen) (LIM domain only protein 4) (LMO-4)
Gene: LMO4

Interactor 2: IKZF1 (Q13422)
DNA-binding protein Ikaros (Ikaros family zinc finger protein 1) (Lymphoid transcription factor LyF-1)
Gene: IKZF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.50	0.553

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 165 Hs			1 519
+	Hs
		1104616 LMO3_HUMAN (13-152): 6.28e-41: 136: 47.86		IKZF1_HUMAN (1-519): 0: 663: 100.00
+	Hs
		681807 RBTN2_HUMAN (23-140): 7.71e-36: 123: 46.61		IKZF1_HUMAN (1-519): 0: 663: 100.00
+	Hs
		682028 RBTN1_HUMAN (1-143): 1.21e-35: 123: 48.25		IKZF1_HUMAN (1-519): 0: 663: 100.00
+	Hs
		1104635 LHX4_HUMAN (82-165): 1.1e-12: 66.2: 18.75		IKZF1_HUMAN (1-519): 0: 663: 100.00
+	Hs
		913832 LMO4_HUMAN (1-165): 8.51e-43: 141: 100.00		ZN135_HUMAN (43-519): 0: 548: 16.36
+	Hs
		903055 LMO3_HUMAN (13-152): 6.28e-41: 136: 47.86		ZNF84_HUMAN (2-416): 9.46e-177: 516: 15.69
+	Hs
		682014 RBTN1_HUMAN (1-143): 1.21e-35: 123: 48.25		ZNF84_HUMAN (2-416): 9.46e-177: 516: 15.69
+	Hs
		965526 LMO4_HUMAN (1-165): 8.51e-43: 141: 100.00		IKZF3_HUMAN (11-515): 8.4e-139: 412: 53.82
+	Hs
		681949 RBTN2_HUMAN (23-140): 7.71e-36: 123: 46.61		IKZF3_HUMAN (11-515): 8.4e-139: 412: 53.82
+	Hs
		682119 RBTN1_HUMAN (1-143): 1.21e-35: 123: 48.25		IKZF3_HUMAN (11-515): 8.4e-139: 412: 53.82
+	Hs
		965520 LMO4_HUMAN (1-165): 8.51e-43: 141: 100.00		RBAK_HUMAN (287-517): 1.56e-24: 109: 10.84
+	Hs
		1347361 LMO3_HUMAN (13-152): 6.28e-41: 136: 47.86		ZIM3_HUMAN (118-224): 2.2e-14: 77.4: 33.65
+	Hs
		965490 LMO4_HUMAN (1-165): 8.51e-43: 141: 100.00		ZN397_HUMAN (118-197): 2.28e-11: 68.2: 37.50
+	Hs
		681870 RBTN2_HUMAN (23-140): 7.71e-36: 123: 46.61		ZNF34_HUMAN (117-224): 1.16e-16: 84.7: 37.04
+	Hs
		1153645 LMO3_HUMAN (13-152): 6.28e-41: 136: 47.86		ZKSC8_HUMAN (118-171): 1.72e-09: 62.4: 51.85
+	Hs
		1434722 PDLI7_HUMAN (16-165): 5.78e-33: 123: 20.99		IKZF5_HUMAN (62-193): 1.16e-11: 68.6: 33.33
+	Dm
		120079 M9PCA3_DROME (19-140): 2.66e-23: 97.1: 44.36		CF2_DROME (117-191): 1.45e-10: 65.5: 41.33
+	Dm
		631823 Q9VTW5_DROME (19-140): 2.49e-23: 97.1: 44.36		CF2_DROME (117-191): 1.45e-10: 65.5: 41.33
+	Hs
		877516 LHX1_HUMAN (12-77): 6.23e-10: 58.5: 23.88		OZF_HUMAN (118-196): 2.31e-12: 69.7: 37.98
+	Hs
		1434726 LHX3_HUMAN (14-78): 6.67e-10: 58.5: 22.73		IKZF5_HUMAN (62-193): 1.16e-11: 68.6: 33.33