HitPredict

Interactor 1: MSHR (Q01726)
Melanocyte-stimulating hormone receptor (MSH-R) (Melanocortin receptor 1) (MC1-R)
Gene: MC1R

Interactor 2: MRAP (Q8TCY5)
Melanocortin-2 receptor accessory protein (B27) (Fat cell-specific low molecular weight protein) (Fat tissue-specific low MW protein)
Gene: MRAP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19329486
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 172
+	Hs
		686595 MC4R_HUMAN (36-315): 8.86e-87: 265: 52.14		MRAP_HUMAN (1-172): 1.25e-115: 326: 100.00
+	Hs
		966341 ACTHR_HUMAN (27-316): 3.4e-78: 242: 39.66		MRAP_HUMAN (1-172): 1.25e-115: 326: 100.00
+	Hs
		702466 MC5R_HUMAN (14-316): 7.03e-62: 201: 45.88		MRAP_HUMAN (1-172): 1.25e-115: 326: 100.00
+	Hs
		785334 MC3R_HUMAN (1-314): 5.93e-59: 193: 45.71		MRAP_HUMAN (1-172): 1.25e-115: 326: 100.00
+	Hs
		686596 MC4R_HUMAN (36-315): 8.86e-87: 265: 52.14		MRAP2_HUMAN (1-71): 6.49e-35: 122: 40.54
+	Hs
		966342 ACTHR_HUMAN (27-316): 3.4e-78: 242: 39.66		MRAP2_HUMAN (1-71): 6.49e-35: 122: 40.54
+	Hs
		702467 MC5R_HUMAN (14-316): 7.03e-62: 201: 45.88		MRAP2_HUMAN (1-71): 6.49e-35: 122: 40.54
+	Hs
		785335 MC3R_HUMAN (1-314): 5.93e-59: 193: 45.71		MRAP2_HUMAN (1-71): 6.49e-35: 122: 40.54
+	Hs
		966353 MSHR_HUMAN (1-317): 1.34e-57: 190: 100.00		MRAP2_HUMAN (1-71): 6.49e-35: 122: 40.54