Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG
Interactor 2: NED4L (Q96PU5)
E3 ubiquitin-protein ligase NEDD4-like (EC 2.3.2.26) (EC 2.3.2.36) (HECT-type E3 ubiquitin transferase NED4L) (NEDD4.2) (Nedd4-2)
Gene: NEDD4L
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.87 | 0.60 | 0.723 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 34294877, 33961781, 36931259, 20936779, 28514442 |
| Identification Methods | unspecified method, affinity chromatography technology, x-ray crystallography, proximity labelling technology, two hybrid, anti tag coimmunoprecipitation, two hybrid pooling approach |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025