HitPredict

Interactor 1: AT2B2 (Q01814)
Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2)
Gene: ATP2B2

Interactor 2: AT2B3 (Q16720)
Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3)
Gene: ATP2B3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cation_ATPase~E1-E2_ATPase, Cation_ATPase_C~Cation_ATPase_C, Cation_ATPase_C~E1-E2_ATPase, Cation_ATPase_C~Hydrolase, Cation_ATPase_N~E1-E2_ATPase, Cation_ATPase_N~Hydrolase, E1-E2_ATPase~E1-E2_ATPase, E1-E2_ATPase~Hydrolase, Hydrolase~Hydrolase
Common GO terms GO:0005388 - P-type calcium transporter activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0016887 - ATP hydrolysis activity
and 9 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1243
Hs

1 1220
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+ Mm
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+ Rn
+ Sc
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+ Sc

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Last updated: 15 Jul 2024