HitPredict

Interactor 1: EWS (Q01844)
RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein)
Gene: EWSR1

Interactor 2: KHDR2 (Q5VWX1)
KH domain-containing, RNA-binding, signal transduction-associated protein 2 (Sam68-like mammalian protein 1) (SLM-1) (hSLM-1)
Gene: KHDRBS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.608

Property	Details
Experiments	16189514, 31515488
Identification Methods	two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 656 Hs			1 349
+	Hs
		267483 FUS_HUMAN (55-545): 1.15e-31: 131: 30.35		KHDR3_HUMAN (3-349): 2e-141: 406: 64.87
+	Hs
		967127 EWS_HUMAN (1-656): 1.54e-47: 179: 100.00		KHDR1_HUMAN (3-349): 4.21e-120: 355: 62.50
+	Hs
		726768 FUS_HUMAN (55-545): 1.15e-31: 131: 30.35		KHDR1_HUMAN (3-349): 4.21e-120: 355: 62.50
+	Hs
		967370 EWS_HUMAN (1-656): 1.54e-47: 179: 100.00		QKI_HUMAN (5-272): 2.33e-89: 273: 33.80
+	Hs
		318700 EYA4_HUMAN (3-271): 6.07e-39: 154: 18.02		QKI_HUMAN (5-272): 2.33e-89: 273: 33.80
+	Hs
		1075712 RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05		SF01_HUMAN (8-209): 6.71e-57: 196: 27.01
+	Hs
		967199 EWS_HUMAN (1-656): 1.54e-47: 179: 100.00		SF01_HUMAN (8-209): 6.71e-57: 196: 27.01
+	Dm
		1371014 Q9VMV5_DROME (3-357): 2.61e-15: 82.2: 12.08		Q9W255_DROME (4-302): 3.79e-88: 272: 37.12
+	Hs
		318624 EYA4_HUMAN (3-271): 6.07e-39: 154: 18.02		SF01_HUMAN (8-209): 6.71e-57: 196: 27.01
+	Hs
		726844 FUS_HUMAN (55-545): 1.15e-31: 131: 30.35		SF01_HUMAN (8-209): 6.71e-57: 196: 27.01