Protein: PGTA
Geranylgeranyl transferase type-2 subunit alpha (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit alpha) (Rab geranyl-geranyltransferase subunit alpha) (Rab GG transferase alpha) (Rab GGTase alpha) (Rab geranylgeranyltransferase subunit alpha)

Gene: PGTA, RABGGTA
Organism: Homo sapiens
Interactions: 66
UniProt ID: Q92696

Gene Ontology (top 5):
GO:0004663 - Rab geranylgeranyltransferase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005968 - Rab-protein geranylgeranyltransferase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

921553

PGTB2
Geranylgeranyl transferase type-2 subunit beta

7

20

High-throughput

0.964

High

664889

RAE1
Rab proteins geranylgeranyltransferase component A 1

5

4

Small-scale

0.716

High

631388

RAB5A
Ras-related protein Rab-5A

5

15

High-throughput

0.712

High

686586

RAE2
Rab proteins geranylgeranyltransferase component A 2

4

4

High-throughput

0.697

High

1116351

RAB31
Ras-related protein Rab-31

4

20

High-throughput

0.691

High

1116374

RAB32
Ras-related protein Rab-32

3

19

High-throughput

0.667

High

1366810

RAB1B
Ras-related protein Rab-1B

3

9

High-throughput

0.667

High

1366813

RAB9B
Ras-related protein Rab-9B

3

20

High-throughput

0.667

High

1366814

RAB6B
Ras-related protein Rab-6B

3

17

High-throughput

0.662

High

170527

RAB7L
Ras-related protein Rab-7L1

2

20

High-throughput

0.628

High

192288

YKT6
Synaptobrevin homolog YKT6

2

2

High-throughput

0.628

High

901983

RAB9A
Ras-related protein Rab-9A

2

20

High-throughput

0.628

High

981334

RAB1A
Ras-related protein Rab-1A

2

12

High-throughput

0.628

High

1366817

LAMP3
Lysosome-associated membrane glycoprotein 3

2

7

High-throughput

0.628

High

630432

RAB3A
Ras-related protein Rab-3A

2

10

High-throughput

0.611

High

900965

RAB5C
Ras-related protein Rab-5C

2

16

High-throughput

0.611

High

226989

ENSA
Alpha-endosulfine

2

0

High-throughput

0.602

High

409017

G3P
Glyceraldehyde-3-phosphate dehydrogenase

2

0

High-throughput

0.602

High

902286

RB27A
Ras-related protein Rab-27A

2

9

High-throughput

0.601

High

967224

RRAS2
Ras-related protein R-Ras2

2

20

High-throughput

0.601

High

1366802

PP16A
Protein phosphatase 1 regulatory subunit 16A

2

6

High-throughput

0.601

High

1153502

RAB30
Ras-related protein Rab-30

2

10

High-throughput

0.574

High

1366800

RAB7B
Ras-related protein Rab-7b

2

20

High-throughput

0.574

High

1366808

DPCD
Protein DPCD

2

1

High-throughput

0.574

High

64695

PALM3
Paralemmin-3

1

1

High-throughput

0.536

High

171297

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

7

High-throughput

0.536

High

181994

UBD
Ubiquitin D

1

6

High-throughput

0.536

High

214231

MCA3
Eukaryotic translation elongation factor 1 epsilon-1

1

1

High-throughput

0.536

High

292465

PALM
Paralemmin-1

1

1

High-throughput

0.536

High

323895

SC31A
Protein transport protein Sec31A

1

1

High-throughput

0.536

High

374823

RASH
GTPase HRas

1

20

High-throughput

0.536

High

469312

ASNS
Asparagine synthetase [glutamine-hydrolyzing]

1

2

High-throughput

0.536

High

909120

NEK4
Serine/threonine-protein kinase Nek4

1

11

High-throughput

0.536

High

938253

SEC13
Protein SEC13 homolog

1

1

High-throughput

0.536

High

1120116

RB33A
Ras-related protein Rab-33A

1

15

High-throughput

0.536

High

1247780

KLH17
Kelch-like protein 17

1

6

High-throughput

0.536

High

1324906

RHG18
Rho GTPase-activating protein 18

1

4

High-throughput

0.536

High

1356526

RAB2B
Ras-related protein Rab-2B

1

14

High-throughput

0.536

High

1366799

RAB24
Ras-related protein Rab-24

1

20

High-throughput

0.536

High

1366807

TBB2B
Tubulin beta-2B chain

1

3

High-throughput

0.536

High

1366811

ES8L2
Epidermal growth factor receptor kinase substrate 8-like protein 2

1

9

High-throughput

0.536

High

1366812

SH24A
SH2 domain-containing protein 4A

1

8

High-throughput

0.536

High

1366815

RAB20
Ras-related protein Rab-20

1

20

High-throughput

0.536

High

1366816

RAB26
Ras-related protein Rab-26

1

10

High-throughput

0.536

High

936202

MANF
Mesencephalic astrocyte-derived neurotrophic factor

1

0

High-throughput

0.513

High

1308273

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

0

High-throughput

0.513

High

1366805

VPS25
Vacuolar protein-sorting-associated protein 25

1

0

High-throughput

0.513

High

1366806

PYM1
Partner of Y14 and mago

1

0

High-throughput

0.513

High

630920

RAB4A
Ras-related protein Rab-4A

1

14

High-throughput

0.489

High

1295416

RAB43
Ras-related protein Rab-43

1

11

High-throughput

0.489

High

1356554

CCD12
Coiled-coil domain-containing protein 12

1

1

High-throughput

0.489

High

242468

PRKN
E3 ubiquitin-protein ligase parkin

1

9

High-throughput

0.479

High

402651

ALDOA
Fructose-bisphosphate aldolase A

1

2

High-throughput

0.479

High

942789

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

5

High-throughput

0.479

High

1254889

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.479

High

390125

ALBU
Albumin

1

0

High-throughput

0.458

High

1334711

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

520705

RRAS
Ras-related protein R-Ras

1

20

High-throughput

0.445

High

955984

RAB8A
Ras-related protein Rab-8A

1

8

Small-scale

0.445

High

957987

RAB14
Ras-related protein Rab-14

1

14

High-throughput

0.445

High

50647

HACL2
2-hydroxyacyl-CoA lyase 2

2

0

High-throughput

0.328

High

369486

AACT
Alpha-1-antichymotrypsin

1

0

High-throughput

0.279

Low

1366803

BT3L4
Transcription factor BTF3 homolog 4

1

0

High-throughput

0.279

Low

1366804

PUS7
Pseudouridylate synthase 7 homolog

1

0

High-throughput

0.279

Low

1366809

RTF2
Replication termination factor 2

1

0

High-throughput

0.279

Low

1366801

T3HPD
Trans-3-hydroxy-L-proline dehydratase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025