HitPredict

Interactor 1: MTF2 (Q02395)
Metal-response element-binding transcription factor 2 (Metal regulatory transcription factor 2) (Metal-response element DNA-binding protein M96) (Polycomb-like protein 2) (mPCl2) (Zinc-regulated factor 1) (ZiRF1)
Gene: MTF2

Interactor 2: EZH2 (Q61188)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2)
Gene: EZH2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.656

The method score is based on:

Property Details
Experiments 20064376, 25680957, 20123894
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001222 - transcription corepressor binding
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 593
Mm

1 746
+ Hs
+ Mm
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+ Mm
+ Hs
+ Mm
+ Hs
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+ Hs
+ Dm
+ Hs
+ Hs
+ Mm
+ Hs
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+ Hs
+ Hs
+ Hs
+ Hs
+ Sp

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Last updated: 15 Jul 2024