HitPredict

Interactor 1: E9PQQ4 (E9PQQ4)
Heat shock protein family A (Hsp70) member 8
Gene: HSPA8

Interactor 2: HS105 (Q92598)
Heat shock protein 105 kDa (Antigen NY-CO-25) (Heat shock 110 kDa protein) (Heat shock protein family H member 1)
Gene: HSPH1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	HSP70~HSP70
Common GO terms	GO:0005524 - ATP binding GO:0140662 - ATP-dependent protein folding chaperone
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 171 Hs			1 858
+	Hs
		537620 HSP7C_HUMAN (1-171): 4.51e-104: 313: 100.00		HS105_HUMAN (1-858): 0: 1003: 100.00
+	Hs
		1198773 Q53FA3_HUMAN (2-171): 4.79e-101: 305: 84.71		HS105_HUMAN (1-858): 0: 1003: 100.00
+	Hs
		343885 HSP7C_HUMAN (1-171): 4.51e-104: 313: 100.00		HS74L_HUMAN (1-858): 0: 952: 57.46
+	Hs
		536610 HSP7C_HUMAN (1-171): 4.51e-104: 313: 100.00		HSP74_HUMAN (1-858): 0: 916: 60.98
+	Hs
		97155 E9PQQ4_HUMAN (1-171): 1.1e-108: 308: 100.00		HSP74_HUMAN (1-858): 0: 916: 60.98
+	Hs
		516184 HS71B_HUMAN (1-171): 5.22e-102: 307: 87.72		HSP74_HUMAN (1-858): 0: 916: 60.98
+	Hs
		761331 HS71L_HUMAN (2-171): 5.28e-101: 305: 84.71		HSP74_HUMAN (1-858): 0: 916: 60.98
+	Hs
		538170 HSP7C_HUMAN (1-171): 4.51e-104: 313: 100.00		HYOU1_HUMAN (1-839): 2.84e-81: 284: 27.41
+	Dm
		391833 HSP72_DROME (5-171): 1.29e-101: 306: 82.64		HSP71_DROME (1-586): 7.66e-79: 270: 32.50
+	Dm
		356611 HSP71_DROME (5-171): 1.57e-101: 306: 82.64		HSP68_DROME (1-434): 1.18e-76: 263: 37.59
+	Dm
		356614 HSP70_DROME (5-171): 1.57e-101: 306: 82.64		HSP68_DROME (1-434): 1.18e-76: 263: 37.59
+	Hs
		536371 HSP7C_HUMAN (1-171): 4.51e-104: 313: 100.00		HSP7C_HUMAN (489-709): 3.98e-32: 135: 11.26
+	Mm
		989233 HSP7C_MOUSE (1-171): 4.23e-104: 313: 100.00		HSP7C_MOUSE (489-709): 8.81e-32: 134: 11.26
+	Hs
		536609 HSP7C_HUMAN (1-171): 4.51e-104: 313: 100.00		HS71L_HUMAN (586-716): 1.44e-30: 130: 20.46
+	Hs
		536447 HSP7C_HUMAN (1-171): 4.51e-104: 313: 100.00		HSP76_HUMAN (604-707): 1.47e-26: 117: 22.86
+	Hs
		600750 HS71L_HUMAN (2-171): 5.28e-101: 305: 84.71		HSP76_HUMAN (604-707): 1.47e-26: 117: 22.86
+	Mm
		609022 HS71A_MOUSE (1-171): 5.16e-101: 305: 87.72		HS71B_MOUSE (586-704): 1.64e-24: 111: 21.67