HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: LUZP1 (Q86V48)
Leucine zipper protein 1 (Filamin mechanobinding actin cross-linking protein) (Fimbacin)
Gene: LUZP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 1076
+	Hs
		773148 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		MYH10_HUMAN (1-608): 3.08e-28: 125: 11.11
+	Hs
		971486 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		ROCK1_HUMAN (83-619): 3.75e-26: 118: 12.09
+	Hs
		776794 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		MYH11_HUMAN (3-537): 2.17e-23: 109: 13.19
+	Hs
		971623 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		MRCKA_HUMAN (226-673): 1.22e-21: 104: 10.11
+	Mm
		98050 1433E_MOUSE (1-255): 4.89e-154: 430: 100.00		DESP_MOUSE (15-572): 4.49e-20: 99.2: 14.78
+	Hs
		971618 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		CCD18_HUMAN (34-415): 8.04e-15: 81.8: 18.69
+	Hs
		971588 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		GRDN_HUMAN (10-513): 1.42e-09: 64.9: 17.82
+	Zm
		5605 B6U284_MAIZE (3-255): 8.26e-147: 412: 70.59		A0A1D6DZK4_MAIZE (307-843): 5.39e-12: 72.5: 10.66