HitPredict

Interactor 1: PAX2 (Q02962)
Paired box protein Pax-2
Gene: PAX2

Interactor 2: PAXI1 (Q6ZW49)
PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein)
Gene: PAXIP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	10908331, 35140242
Identification Methods	affinity chromatography technology, two hybrid, pull down, proximity labelling technology
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 417 Hs			1 1069
+	Mm
		685622 PAX2_MOUSE (1-417): 2.85e-117: 350: 98.32		PAXI1_MOUSE (592-1069): 2.91e-144: 461: 92.47
+	Mm
		971992 PAX5_MOUSE (1-417): 1.19e-98: 301: 63.40		PAXI1_MOUSE (592-1069): 2.91e-144: 461: 92.47
+	Mm
		926110 PAX6_MOUSE (13-417): 4.77e-92: 285: 32.35		PAXI1_MOUSE (592-1069): 2.91e-144: 461: 92.47
+	Mm
		959180 PAX8_MOUSE (9-415): 1.39e-70: 231: 47.17		PAXI1_MOUSE (592-1069): 2.91e-144: 461: 92.47
+	Hs
		641459 PAX6_HUMAN (13-417): 4.77e-92: 285: 32.35		PAXI1_HUMAN (1-419): 4.99e-91: 316: 100.00
+	Hs
		620167 PAX7_HUMAN (16-410): 3.06e-80: 257: 31.83		PAXI1_HUMAN (1-419): 4.99e-91: 316: 100.00
+	Hs
		988775 PAX8_HUMAN (9-415): 2.13e-71: 233: 47.13		PAXI1_HUMAN (1-419): 4.99e-91: 316: 100.00
+	Hs
		878424 PAX9_HUMAN (13-246): 2.63e-54: 185: 45.11		PAXI1_HUMAN (1-419): 4.99e-91: 316: 100.00
+	Hs
		973888 PAX2_HUMAN (1-417): 2.32e-119: 355: 100.00		CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07
+	Hs
		641583 PAX6_HUMAN (13-417): 4.77e-92: 285: 32.35		CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07
+	Hs
		973865 PAX2_HUMAN (1-417): 2.32e-119: 355: 100.00		KMT2C_HUMAN (162-612): 3.03e-12: 73.5: 9.11
+	Hs
		620215 PAX7_HUMAN (16-410): 3.06e-80: 257: 31.83		CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07
+	Hs
		988814 PAX8_HUMAN (9-415): 2.13e-71: 233: 47.13		CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07
+	Hs
		203210 PAX6_HUMAN (13-417): 4.77e-92: 285: 32.35		SYNJ1_HUMAN (308-793): 1.18e-14: 81.2: 10.41
+	Hs
		641482 PAX6_HUMAN (13-417): 4.77e-92: 285: 32.35		KMT2C_HUMAN (162-612): 3.03e-12: 73.5: 9.11
+	Hs
		620175 PAX7_HUMAN (16-410): 3.06e-80: 257: 31.83		KMT2C_HUMAN (162-612): 3.03e-12: 73.5: 9.11
+	Hs
		878473 PAX9_HUMAN (13-246): 2.63e-54: 185: 45.11		CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07
+	Hs
		988783 PAX8_HUMAN (9-415): 2.13e-71: 233: 47.13		KMT2C_HUMAN (162-612): 3.03e-12: 73.5: 9.11
+	Hs
		878440 PAX9_HUMAN (13-246): 2.63e-54: 185: 45.11		KMT2C_HUMAN (162-612): 3.03e-12: 73.5: 9.11