HitPredict

Interactor 1: DYST (Q03001)
Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein)
Gene: DST

Interactor 2: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32877691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 7570 Hs			1 618
+	Hs
		545334 DYST_HUMAN (1-7570): 0: 2600: 100.00		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		974076 DYST_HUMAN (1-7570): 0: 2600: 100.00		RAB35_HUMAN (5-168): 3.51e-76: 242: 24.70
+	Hs
		925215 DYST_HUMAN (1-7570): 0: 2600: 100.00		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Hs
		914020 DYST_HUMAN (1-7570): 0: 2600: 100.00		RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37
+	Hs
		564488 DYST_HUMAN (1-7570): 0: 2600: 100.00		RHOQ_HUMAN (5-169): 2.02e-10: 62.8: 26.26
+	Hs
		545327 SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		892322 SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95		RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22
+	Hs
		893910 SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95		CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54
+	Hs
		963331 SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95		RAB35_HUMAN (5-168): 3.51e-76: 242: 24.70
+	Hs
		950929 SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95		RHOG_HUMAN (3-170): 1.68e-74: 238: 27.47
+	Hs
		925201 SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Hs
		914014 SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95		RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37
+	Hs
		521617 ACTN1_HUMAN (3770-4283): 1.06e-26: 123: 10.00		RHOF_HUMAN (2-167): 3.37e-11: 65.1: 26.67
+	Hs
		120291 ACTN1_HUMAN (3770-4283): 1.06e-26: 123: 10.00		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89
+	Hs
		915613 SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95		RHOB_HUMAN (6-168): 4.57e-13: 70.1: 29.38
+	Hs
		900386 SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		963424 SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95		RHOF_HUMAN (2-167): 3.37e-11: 65.1: 26.67
+	Hs
		436258 SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95		RHOC_HUMAN (6-168): 3.86e-11: 64.3: 28.25
+	Hs
		120393 SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89
+	Hs
		564483 SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95		RHOQ_HUMAN (5-169): 2.02e-10: 62.8: 26.26