HitPredict

Interactor 1: E9PXB7 (E9PXB7)
E3 ubiquitin-protein ligase (EC 2.3.2.26)
Gene: Nedd4l

Interactor 2: 1433S (O70456)
14-3-3 protein sigma (Stratifin)
Gene: Sfn

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16613846
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 835 Mm			1 248
+	Hs
		730838 NED4L_HUMAN (1-835): 0: 944: 95.79		1433S_HUMAN (1-248): 4.86e-154: 429: 97.58
+	Mm
		97731 E9PXB7_MOUSE (1-835): 0: 959: 100.00		1433E_MOUSE (2-247): 1.44e-147: 413: 59.35
+	Mm
		972278 NED4L_MOUSE (1-835): 0: 951: 97.54		1433E_MOUSE (2-247): 1.44e-147: 413: 59.35
+	Hs
		971900 NED4L_HUMAN (1-835): 0: 944: 95.79		1433E_HUMAN (2-247): 1.44e-147: 413: 59.35
+	Hs
		730441 NEDD4_HUMAN (1-835): 0: 846: 60.41		1433S_HUMAN (1-248): 4.86e-154: 429: 97.58
+	Mm
		97733 E9PXB7_MOUSE (1-835): 0: 959: 100.00		1433T_MOUSE (1-238): 1.96e-108: 314: 72.69
+	Hs
		691348 NED4L_HUMAN (1-835): 0: 944: 95.79		1433T_HUMAN (1-238): 2.54e-109: 316: 73.11
+	Hs
		861551 NEDD4_HUMAN (1-835): 0: 846: 60.41		1433E_HUMAN (2-247): 1.44e-147: 413: 59.35
+	Hs
		990624 NED4L_HUMAN (1-835): 0: 944: 95.79		1433Z_HUMAN (1-239): 9.54e-105: 305: 72.39
+	Mm
		97750 E9PXB7_MOUSE (1-835): 0: 959: 100.00		1433B_MOUSE (1-239): 1.04e-98: 289: 68.20
+	Mm
		97730 E9PXB7_MOUSE (1-835): 0: 959: 100.00		1433G_MOUSE (1-242): 5.06e-98: 288: 64.75
+	Mm
		1298422 NED4L_MOUSE (1-835): 0: 951: 97.54		1433B_MOUSE (1-239): 1.04e-98: 289: 68.20
+	Hs
		730162 NED4L_HUMAN (1-835): 0: 944: 95.79		1433B_HUMAN (1-239): 1.6e-99: 291: 68.20
+	Hs
		966766 NED4L_HUMAN (1-835): 0: 944: 95.79		1433G_HUMAN (1-242): 5.06e-98: 288: 64.75
+	Hs
		1049684 NED4L_HUMAN (1-835): 0: 944: 95.79		1433F_HUMAN (2-242): 9.78e-97: 284: 64.61
+	Hs
		690817 NEDD4_HUMAN (1-835): 0: 846: 60.41		1433T_HUMAN (1-238): 2.54e-109: 316: 73.11
+	Hs
		861555 NEDD4_HUMAN (1-835): 0: 846: 60.41		1433Z_HUMAN (1-239): 9.54e-105: 305: 72.39
+	Hs
		729668 NEDD4_HUMAN (1-835): 0: 846: 60.41		1433B_HUMAN (1-239): 1.6e-99: 291: 68.20
+	Hs
		861550 NEDD4_HUMAN (1-835): 0: 846: 60.41		1433G_HUMAN (1-242): 5.06e-98: 288: 64.75
+	Hs
		861580 NEDD4_HUMAN (1-835): 0: 846: 60.41		1433F_HUMAN (2-242): 9.78e-97: 284: 64.61