Interactor 1: ACTA (P62737)
Actin, aortic smooth muscle (EC 3.6.4.-) (Alpha-actin-2) [Cleaved into: Actin, aortic smooth muscle, intermediate form]
Gene: Acta2

Interactor 2: MYH6 (Q02566)
Myosin-6 (Myosin heavy chain 6) (Myosin heavy chain, cardiac muscle alpha isoform) (MyHC-alpha)
Gene: MYH6

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 29199018
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~Myosin_head
Common GO terms GO:0001725 - stress fiber
GO:0005524 - ATP binding
GO:0008217 - regulation of blood pressure
GO:0019901 - protein kinase binding
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 377
Mm

1 1938
+ Hs
+ Rn
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Dm
+ Dm
+ Dm
+ Hs
+ Hs

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Last updated: 11Aug2025