HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: WDR6 (Q9NNW5)
tRNA (34-2'-O)-methyltransferase regulator WDR6 (WD repeat-containing protein 6)
Gene: WDR6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 196 Hs			1 1121
+	Hs
		988733 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		WDR6_HUMAN (1-1121): 0: 749: 100.00
+	Hs
		962518 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		WDR6_HUMAN (1-1121): 0: 749: 100.00
+	Hs
		581307 RAC2_HUMAN (1-196): 4.54e-77: 230: 53.57		WDR6_HUMAN (1-1121): 0: 749: 100.00
+	Hs
		1015813 RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53		WDR6_HUMAN (1-1121): 0: 749: 100.00
+	Hs
		466475 RHOC_HUMAN (1-196): 8.71e-76: 227: 83.16		WDR6_HUMAN (1-1121): 0: 749: 100.00
+	Hs
		953690 RAC3_HUMAN (1-179): 5.41e-75: 225: 57.54		WDR6_HUMAN (1-1121): 0: 749: 100.00
+	Hs
		955630 CDC42_HUMAN (1-196): 7.26e-75: 225: 49.49		WDR6_HUMAN (1-1121): 0: 749: 100.00
+	Hs
		601457 RHOQ_HUMAN (2-195): 6.74e-68: 207: 51.74		WDR6_HUMAN (1-1121): 0: 749: 100.00
+	Hs
		126817 RHOD_HUMAN (7-182): 3.38e-66: 203: 53.98		WDR6_HUMAN (1-1121): 0: 749: 100.00
+	Hs
		961937 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		RACK1_HUMAN (196-523): 2.93e-47: 173: 17.21
+	Hs
		961923 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		WDR5_HUMAN (866-1120): 7e-19: 91.3: 12.55
+	Hs
		466188 RHOC_HUMAN (1-196): 8.71e-76: 227: 83.16		WDR5_HUMAN (866-1120): 7e-19: 91.3: 12.55
+	Hs
		1015655 RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53		FBXW7_HUMAN (603-914): 4.27e-13: 75.6: 13.75
+	Hs
		161709 RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53		APAF_HUMAN (6-104): 4.65e-10: 66.3: 9.35
+	Hs
		126396 RHOD_HUMAN (7-182): 3.38e-66: 203: 53.98		WDR1_HUMAN (759-1077): 6.53e-14: 78.2: 10.33