HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: WRN (Q14191)
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (DNA helicase, RecQ-like type 3) (RecQ protein-like 2) (Werner syndrome protein) [Includes: 3'-5' exonuclease (EC 3.1.-.-); ATP-dependent helicase (EC 5.6.2.4) (DNA 3'-5' helicase WRN)]
Gene: WRN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30804502
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 1432
+	Hs
		316275 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		RECQ5_HUMAN (525-1181): 5.16e-145: 470: 24.96
+	Hs
		979927 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		DDX42_HUMAN (309-900): 1.68e-131: 432: 13.75
+	Hs
		926320 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		BLM_HUMAN (221-1231): 1.52e-120: 412: 20.21
+	Hs
		315404 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		RECQ4_HUMAN (530-878): 2.43e-118: 402: 29.95
+	Hs
		979881 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		DDX46_HUMAN (278-1201): 2.37e-116: 392: 12.54
+	Hs
		141408 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		DDX3X_HUMAN (354-901): 2.15e-117: 385: 14.68
+	Hs
		980084 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		DDX17_HUMAN (469-955): 7.23e-116: 383: 16.54
+	Hs
		608533 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		DDX5_HUMAN (469-897): 9.25e-111: 365: 16.78