HitPredict

Interactor 1: TLE3 (Q04726)
Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3)
Gene: TLE3

Interactor 2: NFIA (Q12857)
Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein)
Gene: NFIA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35140242, 37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 772 Hs			1 509
+	Hs
		980754 TLE3_HUMAN (1-772): 0: 583: 100.00		NFIX_HUMAN (1-508): 9.66e-154: 449: 67.32
+	Hs
		980594 TLE1_HUMAN (1-772): 0: 538: 77.42		NFIA_HUMAN (1-509): 1.11e-161: 470: 100.00
+	Hs
		980606 TLE1_HUMAN (1-772): 0: 538: 77.42		NFIX_HUMAN (1-508): 9.66e-154: 449: 67.32
+	Hs
		443171 TLE3_HUMAN (1-772): 0: 583: 100.00		NFIC_HUMAN (3-509): 2.94e-130: 390: 57.61
+	Hs
		135107 TLE3_HUMAN (1-772): 0: 583: 100.00		NFIB_HUMAN (1-413): 8.24e-127: 378: 61.41
+	Hs
		443170 TLE1_HUMAN (1-772): 0: 538: 77.42		NFIC_HUMAN (3-509): 2.94e-130: 390: 57.61
+	Hs
		135106 TLE1_HUMAN (1-772): 0: 538: 77.42		NFIB_HUMAN (1-413): 8.24e-127: 378: 61.41
+	Hs
		993404 TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19		NFIA_HUMAN (1-509): 1.11e-161: 470: 100.00
+	Hs
		993425 TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19		NFIX_HUMAN (1-508): 9.66e-154: 449: 67.32
+	Hs
		135111 TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19		NFIB_HUMAN (1-413): 8.24e-127: 378: 61.41
+	Hs
		443244 TBL1R_HUMAN (571-771): 3.06e-46: 174: 15.07		NFIC_HUMAN (3-509): 2.94e-130: 390: 57.61
+	Hs
		135156 TBL1R_HUMAN (571-771): 3.06e-46: 174: 15.07		NFIB_HUMAN (1-413): 8.24e-127: 378: 61.41
+	Hs
		1018252 SNR40_HUMAN (509-677): 5.35e-09: 60.8: 26.52		NFIA_HUMAN (1-509): 1.11e-161: 470: 100.00
+	Hs
		443230 SNR40_HUMAN (509-677): 5.35e-09: 60.8: 26.52		NFIC_HUMAN (3-509): 2.94e-130: 390: 57.61
+	Hs
		123919 TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19		SPT5H_HUMAN (181-357): 1.9e-09: 62.6: 15.76
+	Hs
		124015 POC1A_HUMAN (325-603): 2.33e-51: 186: 14.59		SPT5H_HUMAN (181-357): 1.9e-09: 62.6: 15.76
+	Hs
		302275 WDR5_HUMAN (284-560): 2.42e-32: 130: 9.12		SC31A_HUMAN (222-499): 9.02e-21: 98.4: 12.06
+	Hs
		903374 WDR5_HUMAN (284-560): 2.42e-32: 130: 9.12		KMT2C_HUMAN (183-506): 4.24e-10: 64.9: 9.12
+	Mm
		903669 WDR5_MOUSE (284-560): 2.42e-32: 130: 9.12		KMT2C_MOUSE (188-505): 2.88e-09: 62.2: 15.09
+	Hs
		124040 SNR40_HUMAN (509-677): 5.35e-09: 60.8: 26.52		SPT5H_HUMAN (181-357): 1.9e-09: 62.6: 15.76