HitPredict

Interactor 1: ACVR1 (Q04771)
Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)
Gene: ACVR1

Interactor 2: LRIQ1 (Q96JM4)
Leucine-rich repeat and IQ domain-containing protein 1
Gene: LRRIQ1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.726

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LRR_8~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 509 Hs			1 1722
+	At
		1325025 BRL3_ARATH (50-507): 1.28e-143: 443: 16.52		PXL1_ARATH (785-1345): 3.99e-93: 328: 14.19
+	At
		1114726 BRL1_ARATH (39-507): 3.02e-145: 447: 17.16		ERECT_ARATH (834-1396): 4.55e-89: 315: 15.35
+	At
		221817 BRL1_ARATH (39-507): 3.02e-145: 447: 17.16		BAME1_ARATH (775-1219): 9.59e-71: 260: 12.57
+	At
		221790 BRL3_ARATH (50-507): 1.28e-143: 443: 16.52		BAME1_ARATH (775-1219): 9.59e-71: 260: 12.57
+	At
		186954 BRI1_ARATH (58-499): 4.76e-137: 426: 17.54		BAME1_ARATH (775-1219): 9.59e-71: 260: 12.57
+	At
		1338256 BRL3_ARATH (50-507): 1.28e-143: 443: 16.52		MIK1_ARATH (811-1160): 6.37e-55: 212: 14.62
+	At
		1324089 BRL1_ARATH (39-507): 3.02e-145: 447: 17.16		FLS2_ARATH (1002-1331): 2.68e-46: 185: 14.09
+	At
		1324071 BRL3_ARATH (50-507): 1.28e-143: 443: 16.52		FLS2_ARATH (1002-1331): 2.68e-46: 185: 14.09
+	At
		84606 BRL3_ARATH (50-507): 1.28e-143: 443: 16.52		RGI3_ARATH (1049-1533): 1.31e-35: 150: 14.72
+	At
		1338257 BRL3_ARATH (50-507): 1.28e-143: 443: 16.52		BAME2_ARATH (1072-1535): 4.09e-35: 148: 13.60
+	At
		186952 BRI1_ARATH (58-499): 4.76e-137: 426: 17.54		BRI1_ARATH (704-1079): 3.09e-36: 152: 16.12
+	At
		84587 BRI1_ARATH (58-499): 4.76e-137: 426: 17.54		RGI3_ARATH (1049-1533): 1.31e-35: 150: 14.72
+	At
		1167645 BRL1_ARATH (39-507): 3.02e-145: 447: 17.16		ERL2_ARATH (811-1061): 1.18e-28: 127: 14.89
+	At
		84597 BAK1_ARATH (43-508): 4.98e-142: 423: 18.24		RGI3_ARATH (1049-1533): 1.31e-35: 150: 14.72
+	At
		1167634 BRL3_ARATH (50-507): 1.28e-143: 443: 16.52		ERL2_ARATH (811-1061): 1.18e-28: 127: 14.89
+	At
		83975 BAK1_ARATH (43-508): 4.98e-142: 423: 18.24		Y1743_ARATH (777-1211): 2.27e-31: 136: 12.88
+	At
		186962 BRI1_ARATH (58-499): 4.76e-137: 426: 17.54		ERL2_ARATH (811-1061): 1.18e-28: 127: 14.89
+	At
		84744 BAK1_ARATH (43-508): 4.98e-142: 423: 18.24		Y4361_ARATH (1107-1336): 7.9e-21: 102: 11.48
+	Zm
		111843 K7V4X2_MAIZE (44-509): 1.26e-138: 429: 18.30		K7V4X2_MAIZE (1054-1309): 1.19e-17: 91.9: 15.65
+	At
		1323498 BRL3_ARATH (50-507): 1.28e-143: 443: 16.52		TDR_ARATH (804-946): 3.3e-11: 70.6: 16.11