HitPredict

Interactor 1: RAP1A (P62834)
Ras-related protein Rap-1A (EC 3.6.5.2) (C21KG) (G-22K) (GTP-binding protein smg p21A) (Ras-related protein Krev-1)
Gene: RAP1A

Interactor 2: IFT22 (Q9H7X7)
Intraflagellar transport protein 22 homolog (Rab-like protein 5)
Gene: IFT22

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 184 Hs			1 185
+	Dm
		197040 RAP1_DROME (1-166): 5.58e-83: 244: 89.76		O18332_DROME (4-172): 1.48e-66: 203: 14.04
+	Zm
		77342 B4FAE1_MAIZE (4-180): 6.4e-78: 232: 34.83		B4FAE1_MAIZE (4-176): 2.74e-70: 213: 17.14
+	Mm
		1424002 RAB13_MOUSE (4-183): 3.66e-77: 230: 33.85		RAB1B_MOUSE (4-172): 1.43e-67: 206: 15.21
+	Hs
		981254 RAB1A_HUMAN (4-183): 3.37e-75: 226: 31.49		RAB1A_HUMAN (4-172): 4.07e-68: 208: 14.62
+	Hs
		981357 RAB1A_HUMAN (4-183): 3.37e-75: 226: 31.49		RAB1B_HUMAN (4-172): 1.08e-67: 206: 14.62
+	Mm
		981416 RAB1A_MOUSE (4-183): 3.37e-75: 226: 31.49		RAB1B_MOUSE (4-172): 1.43e-67: 206: 15.21
+	Hs
		976188 RB11A_HUMAN (4-178): 6.32e-73: 220: 28.41		RAB1A_HUMAN (4-172): 4.07e-68: 208: 14.62
+	Hs
		955910 RAB1A_HUMAN (4-183): 3.37e-75: 226: 31.49		RAB8A_HUMAN (4-177): 2.98e-64: 198: 15.91
+	Hs
		1370778 RAB1B_HUMAN (4-179): 1.28e-74: 224: 30.51		RAB8B_HUMAN (4-177): 1e-64: 199: 16.48
+	Hs
		955907 RB11A_HUMAN (4-178): 6.32e-73: 220: 28.41		RAB8A_HUMAN (4-177): 2.98e-64: 198: 15.91
+	Hs
		959312 RAP1B_HUMAN (1-184): 1.22e-76: 228: 95.11		ARF6_HUMAN (3-145): 3.72e-54: 171: 17.48
+	Hs
		974968 RAB1A_HUMAN (4-183): 3.37e-75: 226: 31.49		ARF6_HUMAN (3-145): 3.72e-54: 171: 17.48
+	Hs
		975232 RAB1B_HUMAN (4-179): 1.28e-74: 224: 30.51		ARF6_HUMAN (3-145): 3.72e-54: 171: 17.48
+	Dm
		197051 O18332_DROME (4-180): 1.39e-73: 221: 33.71		ARF1_DROME (3-147): 7.17e-55: 173: 20.00
+	Hs
		976200 RB11A_HUMAN (4-178): 6.32e-73: 220: 28.41		ARF1_HUMAN (3-147): 9.44e-55: 173: 20.00
+	Hs
		974966 RB11A_HUMAN (4-178): 6.32e-73: 220: 28.41		ARF6_HUMAN (3-145): 3.72e-54: 171: 17.48
+	Dm
		197048 O18332_DROME (4-180): 1.39e-73: 221: 33.71		ARF4_DROME (3-145): 2.28e-53: 169: 21.68
+	Hs
		612190 RB11A_HUMAN (4-178): 6.32e-73: 220: 28.41		ARF4_HUMAN (3-145): 1.16e-32: 116: 20.98