HitPredict

Interactor 1: KPCZ (Q05513)
Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)
Gene: PRKCZ

Interactor 2: LIPB1 (Q86W92)
Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2)
Gene: PPFIBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~SAM_1
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 592 Hs			1 1011
+	Hs
		568724 KAPCA_HUMAN (219-578): 5.07e-143: 419: 33.06		LIPB1_HUMAN (1-1011): 7.51e-135: 433: 100.00
+	Hs
		518859 KPCZ_HUMAN (1-592): 0: 688: 100.00		TPR_HUMAN (70-620): 8.21e-09: 62.3: 10.65
+	Hs
		681696 AKT1_HUMAN (172-582): 1.55e-153: 451: 36.39		MYH9_HUMAN (2-781): 5.58e-30: 131: 7.15
+	Hs
		568567 KAPCA_HUMAN (219-578): 5.07e-143: 419: 33.06		MYH9_HUMAN (2-781): 5.58e-30: 131: 7.15
+	Hs
		568568 KAPCA_HUMAN (219-578): 5.07e-143: 419: 33.06		MYH10_HUMAN (2-784): 3.65e-29: 128: 8.24
+	Hs
		116964 SGK1_HUMAN (199-583): 7.41e-144: 424: 38.36		MYH1_HUMAN (185-793): 7.46e-20: 98: 9.05
+	Hs
		518814 KAPCA_HUMAN (219-578): 5.07e-143: 419: 33.06		TPR_HUMAN (70-620): 8.21e-09: 62.3: 10.65
+	Hs
		724784 KPCE_HUMAN (6-196): 1.52e-27: 120: 19.02		MYH9_HUMAN (2-781): 5.58e-30: 131: 7.15
+	Mm
		554927 KPCE_MOUSE (6-190): 3.27e-27: 118: 18.91		MYH7_MOUSE (185-793): 1.22e-21: 104: 8.72
+	Mm
		554901 KPCE_MOUSE (6-190): 3.27e-27: 118: 18.91		MYH6_MOUSE (185-793): 5.52e-21: 101: 8.56