HitPredict

Interactor 1: GBB2 (P62879)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (G protein subunit beta-2) (Transducin beta chain 2)
Gene: GNB2

Interactor 2: PHLP (Q13371)
Phosducin-like protein (PHLP)
Gene: PDCL

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	28514442, 33961781, 37689310, 19376773
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 340 Hs			1 301
+	Hs
		1103660 GBB4_HUMAN (1-340): 7.17e-109: 322: 90.00		PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00
+	Hs
		597358 GBB3_HUMAN (1-340): 3.82e-105: 313: 80.88		PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00
+	Hs
		983470 GBB1_HUMAN (1-340): 2.39e-105: 313: 90.29		PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00
+	Dm
		684604 GBB1_DROME (1-340): 1.42e-105: 314: 81.47		PHLP1_DROME (1-277): 9.43e-89: 267: 44.41
+	Bt
		624601 GBB1_BOVIN (1-340): 2.39e-105: 313: 90.29		PHOS_BOVIN (51-291): 6.22e-75: 231: 46.89
+	Hs
		984274 GBB2_HUMAN (1-340): 3.43e-110: 326: 100.00		PDCL3_HUMAN (74-301): 5.7e-67: 210: 26.78
+	Hs
		983572 GBB1_HUMAN (1-340): 2.39e-105: 313: 90.29		PDCL3_HUMAN (74-301): 5.7e-67: 210: 26.78
+	Ce
		604389 GBB1_CAEEL (1-340): 2.72e-105: 313: 85.29		Q9U1X7_CAEEL (4-269): 1.7e-59: 192: 27.14
+	Hs
		163636 GNB5_HUMAN (129-340): 7.58e-44: 157: 20.81		PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00
+	Hs
		155747 GBB2_HUMAN (1-340): 3.43e-110: 326: 100.00		TXND9_HUMAN (104-287): 1.43e-50: 168: 18.85
+	Hs
		1103638 POC1A_HUMAN (16-125): 3.54e-24: 103: 18.42		PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00
+	Sc
		617416 GBB_YEAST (2-340): 5.31e-76: 241: 36.01		PLP1_YEAST (97-301): 2.52e-45: 154: 20.36
+	Sc
		617417 GBB_YEAST (2-340): 5.31e-76: 241: 36.01		PLP2_YEAST (71-301): 1.51e-43: 152: 15.66
+	Hs
		1334170 POC1A_HUMAN (16-125): 3.54e-24: 103: 18.42		PDCL3_HUMAN (74-301): 5.7e-67: 210: 26.78
+	Hs
		155783 POC1A_HUMAN (16-125): 3.54e-24: 103: 18.42		TXND9_HUMAN (104-287): 1.43e-50: 168: 18.85