HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: SREC2 (Q96GP6)
Scavenger receptor class F member 2 (SRECRP-1) (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II)
Gene: SCARF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 871
+	Hs
		594078 NCK1_HUMAN (5-145): 9.5e-23: 96.3: 33.14		SREC2_HUMAN (1-871): 7.69e-107: 351: 100.00
+	Hs
		362346 ABL1_HUMAN (4-139): 4.41e-22: 95.5: 35.46		SREC2_HUMAN (1-871): 7.69e-107: 351: 100.00
+	Hs
		440676 FYN_HUMAN (161-215): 9.09e-13: 68.5: 31.58		SREC2_HUMAN (1-871): 7.69e-107: 351: 100.00
+	Mm
		1039132 GRB2_MOUSE (1-217): 5.96e-71: 217: 99.54		TIE2_MOUSE (112-221): 5.52e-12: 72: 30.99
+	Hs
		551610 GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00		NFH_HUMAN (534-762): 1.38e-10: 67.2: 15.32
+	Hs
		463258 YES_HUMAN (71-215): 7.5e-12: 65.8: 16.33		TEN1_HUMAN (2-281): 1.41e-43: 174: 20.12
+	Hs
		463125 YES_HUMAN (71-215): 7.5e-12: 65.8: 16.33		PEAR1_HUMAN (1-402): 2.21e-36: 150: 27.23
+	Hs
		594135 NCK1_HUMAN (5-145): 9.5e-23: 96.3: 33.14		NOTC3_HUMAN (7-463): 6.21e-21: 101: 15.78
+	Hs
		362408 ABL1_HUMAN (4-139): 4.41e-22: 95.5: 35.46		NOTC3_HUMAN (7-463): 6.21e-21: 101: 15.78
+	Dm
		262710 ABL_DROME (4-135): 1.01e-22: 97.4: 37.68		TENM_DROME (8-138): 4.07e-15: 82.5: 14.67
+	Hs
		1396023 ITSN2_HUMAN (108-216): 6.53e-13: 69.2: 18.92		MEG10_HUMAN (318-616): 1.19e-15: 84: 13.59
+	Hs
		440680 FYN_HUMAN (161-215): 9.09e-13: 68.5: 31.58		MEG10_HUMAN (318-616): 1.19e-15: 84: 13.59
+	Hs
		319045 LYN_HUMAN (129-215): 1.97e-09: 58.5: 22.47		K0754_HUMAN (634-870): 2.79e-15: 82.9: 17.41