HitPredict

Interactor 1: DESP (P15924)
Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen)
Gene: DSP

Interactor 2: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21319273
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 2871 Hs			1 298
+	Hs
		414713 DESP_HUMAN (1-2871): 0: 818: 100.00		CDK1_HUMAN (1-289): 7.44e-144: 408: 66.90
+	Hs
		625446 PLEC_HUMAN (20-1265): 9.18e-42: 172: 9.33		CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00
+	Hs
		414820 CENPF_HUMAN (11-1800): 6.64e-55: 215: 10.64		CDK1_HUMAN (1-289): 7.44e-144: 408: 66.90
+	Hs
		625418 SPTN1_HUMAN (235-2163): 6.27e-28: 126: 9.67		CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00
+	Hs
		528401 MYH8_HUMAN (45-861): 4.24e-26: 120: 9.54		CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00
+	Hs
		625380 DYST_HUMAN (91-2218): 3.51e-25: 118: 10.10		CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00
+	Hs
		960128 MYH2_HUMAN (1590-2502): 7.34e-35: 149: 11.14		CDK3_HUMAN (1-294): 1.8e-154: 435: 76.87
+	Hs
		522542 MYH1_HUMAN (24-969): 1.33e-34: 148: 9.08		CDK3_HUMAN (1-294): 1.8e-154: 435: 76.87
+	Hs
		528405 MYH8_HUMAN (45-861): 4.24e-26: 120: 9.54		CDK3_HUMAN (1-294): 1.8e-154: 435: 76.87
+	Hs
		960129 MYH13_HUMAN (1490-2045): 1e-24: 116: 13.84		CDK3_HUMAN (1-294): 1.8e-154: 435: 76.87
+	Hs
		522604 MYH7_HUMAN (38-718): 1.99e-21: 105: 8.44		CDK3_HUMAN (1-294): 1.8e-154: 435: 76.87
+	Hs
		625369 SPTB2_HUMAN (1169-2330): 8.03e-10: 67.2: 8.93		CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00
+	Hs
		528368 MYH6_HUMAN (1555-2052): 9.12e-19: 96.5: 14.03		CDK3_HUMAN (1-294): 1.8e-154: 435: 76.87
+	Hs
		502908 MYH3_HUMAN (1718-2000): 3.6e-10: 68.4: 15.19		CDK3_HUMAN (1-294): 1.8e-154: 435: 76.87
+	Hs
		841168 SPTB2_HUMAN (1169-2330): 8.03e-10: 67.2: 8.93		CDK7_HUMAN (2-298): 9.81e-124: 359: 44.00