HitPredict

Interactor 1: F1M7H2 (F1M7H2)
Polymeric immunoglobulin receptor
Gene: Pigr

Interactor 2: INSR (P15127)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Species: Rattus norvegicus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	30300385
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	V-set~fn3, Furin-like~V-set, Recep_L_domain~V-set
Common GO terms	GO:0005886 - plasma membrane GO:0043235 - receptor complex
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 781 Rn			1 1383
+	Hs
		564802 NCAM1_HUMAN (16-613): 4.33e-77: 268: 15.27		EPHA3_HUMAN (661-1320): 1.12e-174: 548: 24.01
+	Hs
		710600 ROBO1_HUMAN (443-666): 3.59e-11: 69.3: 14.59		EPHA2_HUMAN (662-1354): 1.63e-170: 536: 23.02
+	Hs
		710503 ROBO2_HUMAN (27-407): 2.2e-10: 66.6: 10.64		EPHA2_HUMAN (662-1354): 1.63e-170: 536: 23.02
+	Hs
		411278 NCAM1_HUMAN (16-613): 4.33e-77: 268: 15.27		NTRK1_HUMAN (997-1287): 1.61e-65: 240: 41.95
+	Hs
		362680 NCAM1_HUMAN (16-613): 4.33e-77: 268: 15.27		EGFR_HUMAN (32-308): 6.63e-31: 134: 22.19
+	Hs
		412363 PXDN_HUMAN (20-353): 3.82e-40: 162: 16.42		NTRK1_HUMAN (997-1287): 1.61e-65: 240: 41.95
+	Mm
		564867 NCAM1_MOUSE (360-637): 1.92e-19: 95.9: 13.62		NTRK2_MOUSE (997-1293): 1.65e-66: 244: 42.38
+	Hs
		1462024 ROBO1_HUMAN (443-666): 3.59e-11: 69.3: 14.59		ALK_HUMAN (997-1340): 6.15e-71: 264: 41.57
+	Hs
		1439197 ROBO2_HUMAN (27-407): 2.2e-10: 66.6: 10.64		ALK_HUMAN (997-1340): 6.15e-71: 264: 41.57
+	Hs
		412342 TITIN_HUMAN (152-590): 1.12e-09: 64.7: 10.74		NTRK1_HUMAN (997-1287): 1.61e-65: 240: 41.95
+	Hs
		69608 CLM7_HUMAN (363-482): 2.01e-37: 140: 19.67		EGFR_HUMAN (32-308): 6.63e-31: 134: 22.19
+	Hs
		363641 TITIN_HUMAN (152-590): 1.12e-09: 64.7: 10.74		EGFR_HUMAN (32-308): 6.63e-31: 134: 22.19