HitPredict

Interactor 1: FMR1 (Q06787)
Fragile X messenger ribonucleoprotein 1 (Fragile X messenger ribonucleoprotein) (FMRP) (Protein FMR-1)
Gene: FMR1

Interactor 2: SERB1 (Q8NC51)
SERPINE1 mRNA-binding protein 1 (PAI1 RNA-binding protein 1) (PAI-RBP1) (Plasminogen activator inhibitor 1 RNA-binding protein)
Gene: SERBP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

The method score is based on:

Property	Details
Experiments	34079125, 32525608, 24205981
Identification Methods	proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003730 - mRNA 3'-UTR binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol and 6 others more... GO:0016020 - membrane GO:0017148 - negative regulation of translation GO:0030371 - translation repressor activity GO:0043022 - ribosome binding GO:0043488 - regulation of mRNA stability GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	632
Hs

1	408

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024