HitPredict

Interactor 1: FMR1 (Q06787)
Fragile X messenger ribonucleoprotein 1 (Fragile X messenger ribonucleoprotein) (FMRP) (Protein FMR-1)
Gene: FMR1

Interactor 2: FUBP3 (Q96I24)
Far upstream element-binding protein 3 (FUSE-binding protein 3)
Gene: FUBP3

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	29395067, 26949739
Identification Methods	proximity labelling technology, affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	KH_1~KH_1
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 1 others more... GO:0016020 - membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 632 Hs			1 572
+	Hs
		989047 FMR1_HUMAN (1-632): 0: 1106: 100.00		FUBP1_HUMAN (16-565): 1.97e-104: 329: 52.53
+	Mm
		729463 FMR1_MOUSE (1-632): 0: 1063: 93.99		FUBP2_MOUSE (14-558): 1.81e-106: 338: 42.36
+	Hs
		128147 FMR1_HUMAN (1-632): 0: 1106: 100.00		IF2B3_HUMAN (237-560): 9.9e-32: 131: 14.15
+	Hs
		989156 FMR1_HUMAN (1-632): 0: 1106: 100.00		IF2B1_HUMAN (237-560): 7.9e-26: 113: 15.69
+	Hs
		903897 FMR1_HUMAN (1-632): 0: 1106: 100.00		HNRPK_HUMAN (242-475): 5.55e-18: 88.8: 15.26
+	Hs
		989222 FMR1_HUMAN (1-632): 0: 1106: 100.00		IF2B2_HUMAN (233-445): 1.04e-12: 72.6: 18.14
+	Mm
		729432 FMR1_MOUSE (1-632): 0: 1063: 93.99		PCBP1_MOUSE (21-151): 5.83e-13: 72.3: 23.88
+	Hs
		843848 FXR1_HUMAN (1-334): 0: 604: 73.95		FUBP3_HUMAN (1-572): 4.37e-163: 478: 100.00
+	Mm
		1112169 Q8BPK8_MOUSE (1-357): 0: 688: 97.76		FUBP2_MOUSE (14-558): 1.81e-106: 338: 42.36
+	Hs
		843831 FXR1_HUMAN (1-334): 0: 604: 73.95		FUBP1_HUMAN (16-565): 1.97e-104: 329: 52.53
+	Mm
		888821 Q8BPK8_MOUSE (1-357): 0: 688: 97.76		PCBP1_MOUSE (21-151): 5.83e-13: 72.3: 23.88
+	Mm
		904263 FXR1_MOUSE (1-334): 0: 596: 73.65		HNRPK_MOUSE (242-475): 5.55e-18: 88.8: 15.26
+	Hs
		844194 FXR2_HUMAN (268-525): 3.17e-50: 186: 30.56		FUBP3_HUMAN (1-572): 4.37e-163: 478: 100.00
+	Hs
		844181 FXR2_HUMAN (268-525): 3.17e-50: 186: 30.56		FUBP1_HUMAN (16-565): 1.97e-104: 329: 52.53
+	Hs
		844076 FXR2_HUMAN (268-525): 3.17e-50: 186: 30.56		PCBP1_HUMAN (21-151): 5.83e-13: 72.3: 23.88