HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: GCC2 (Q8IWJ2)
GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) (GCC185) (CLL-associated antigen KW-11) (CTCL tumor antigen se1-1) (Ran-binding protein 2-like 4) (RanBP2L4) (Renal carcinoma antigen NY-REN-53)
Gene: GCC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1684
+	Hs
		971751 1433E_HUMAN (2-241): 9.95e-144: 403: 68.18		GCC2_HUMAN (1-1684): 2.12e-119: 417: 100.00
+	Hs
		772728 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH9_HUMAN (712-1684): 3.25e-42: 172: 11.36
+	Mm
		989976 1433Z_MOUSE (1-245): 3.49e-145: 407: 99.59		MYH10_MOUSE (1-1018): 2.93e-39: 163: 11.44
+	Hs
		990855 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH2_HUMAN (708-1682): 3.59e-40: 165: 12.77
+	Mm
		990028 1433Z_MOUSE (1-245): 3.49e-145: 407: 99.59		MYH9_MOUSE (866-1681): 2.86e-38: 159: 11.61
+	Zm
		5605 B6U284_MAIZE (1-241): 1.06e-142: 401: 63.27		A0A1D6DZK4_MAIZE (851-1684): 4.97e-38: 158: 11.77
+	Hs
		776800 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH11_HUMAN (952-1682): 3.92e-36: 152: 12.43
+	Hs
		776794 1433E_HUMAN (2-241): 9.95e-144: 403: 68.18		MYH11_HUMAN (952-1682): 3.92e-36: 152: 12.43
+	Hs
		990678 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		CP250_HUMAN (1-1122): 3.75e-34: 146: 10.68
+	Hs
		971946 1433E_HUMAN (2-241): 9.95e-144: 403: 68.18		CP250_HUMAN (1-1122): 3.75e-34: 146: 10.68
+	Hs
		990235 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		NUMA1_HUMAN (740-1684): 2.62e-31: 136: 11.81
+	Hs
		773148 1433E_HUMAN (2-241): 9.95e-144: 403: 68.18		MYH10_HUMAN (1-891): 5.4e-30: 132: 13.09
+	Mm
		990062 1433Z_MOUSE (1-245): 3.49e-145: 407: 99.59		PLEC_MOUSE (1-812): 3.16e-18: 94.2: 11.15
+	Hs
		556912 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH7_HUMAN (1-602): 3.34e-18: 93.8: 12.10
+	Hs
		556897 1433T_HUMAN (1-245): 2.61e-140: 395: 79.59		MYH7_HUMAN (1-602): 3.34e-18: 93.8: 12.10
+	Hs
		535929 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH3_HUMAN (1-520): 2.82e-13: 77.7: 10.17
+	Hs
		990856 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH13_HUMAN (1298-1684): 1.19e-10: 69.2: 10.85
+	Hs
		990250 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PLEC_HUMAN (15-463): 1.65e-10: 68.8: 11.21
+	Hs
		990814 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		DAPLE_HUMAN (582-1406): 5.97e-09: 63.5: 20.77
+	Hs
		972083 1433E_HUMAN (2-241): 9.95e-144: 403: 68.18		DAPLE_HUMAN (582-1406): 5.97e-09: 63.5: 20.77