Protein: GCC2
GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) (GCC185) (CLL-associated antigen KW-11) (CTCL tumor antigen se1-1) (Ran-binding protein 2-like 4) (RanBP2L4) (Renal carcinoma antigen NY-REN-53)

Gene: GCC2
Organism: Homo sapiens
Interactions: 127
UniProt ID: Q8IWJ2

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005794 - Golgi apparatus
GO:0005802 - trans-Golgi network
GO:0005829 - cytosol
GO:0006622 - protein targeting to lysosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

827223

ARL1
ADP-ribosylation factor-like protein 1

3

8

Small-scale

0.835

High

827299

ARL4A
ADP-ribosylation factor-like protein 4A

1

16

Small-scale

0.713

High

631669

RAB6A
Ras-related protein Rab-6A

1

13

Small-scale

0.692

High

346658

TTC4
Tetratricopeptide repeat protein 4

4

14

High-throughput

0.691

High

1310151

GCC2
GRIP and coiled-coil domain-containing protein 2

1

16

Small-scale

0.665

High

252881

EXOC3
Exocyst complex component 3

3

4

High-throughput

0.662

High

1310179

ZRAN1
Ubiquitin thioesterase ZRANB1

3

20

High-throughput

0.656

High

703639

MK01
Mitogen-activated protein kinase 1

3

5

High-throughput

0.650

High

51365

SRCRL
Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D

2

8

High-throughput

0.628

High

968983

PRS8
26S proteasome regulatory subunit 8

2

5

High-throughput

0.628

High

1310170

SYNCI
Syncoilin

2

10

High-throughput

0.628

High

901922

RAB9A
Ras-related protein Rab-9A

1

12

High-throughput

0.618

High

956378

RAB2A
Ras-related protein Rab-2A

1

11

High-throughput

0.618

High

976395

RB11A
Ras-related protein Rab-11A

1

5

High-throughput

0.618

High

1310159

GOGA1
Golgin subfamily A member 1

1

19

High-throughput

0.618

High

1240747

PMF1
Polyamine-modulated factor 1

2

1

High-throughput

0.611

High

1310184

WASC3
WASH complex subunit 3

3

2

High-throughput

0.604

High

1310157

CC107
Coiled-coil domain-containing protein 107

2

0

High-throughput

0.602

High

246740

KDM1A
Lysine-specific histone demethylase 1A

2

6

High-throughput

0.584

High

1109872

HDAC1
Histone deacetylase 1

2

20

High-throughput

0.584

High

936560

AF17
Protein AF-17

2

6

High-throughput

0.574

High

1310155

TCP1L
T-complex protein 10A homolog 1

2

2

High-throughput

0.574

High

1310163

CC136
Coiled-coil domain-containing protein 136

2

19

High-throughput

0.574

High

630874

RAB4A
Ras-related protein Rab-4A

1

12

High-throughput

0.553

High

900907

RAB5C
Ras-related protein Rab-5C

1

12

High-throughput

0.553

High

270954

CLAP2
CLIP-associating protein 2

1

4

High-throughput

0.536

High

503621

TFPT
TCF3 fusion partner

1

3

High-throughput

0.536

High

634512

LMNB1
Lamin-B1

1

13

High-throughput

0.536

High

730035

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.536

High

966582

1433G
14-3-3 protein gamma

1

20

High-throughput

0.536

High

971751

1433E
14-3-3 protein epsilon

1

5

High-throughput

0.536

High

990466

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

997413

TBB4B
Tubulin beta-4B chain

1

6

High-throughput

0.536

High

1098053

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

2

High-throughput

0.536

High

1110491

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

1

High-throughput

0.536

High

1152146

MARE1
Microtubule-associated protein RP/EB family member 1

1

6

High-throughput

0.536

High

1278191

CLAP1
CLIP-associating protein 1

1

4

High-throughput

0.536

High

1310156

BRK1
Protein BRICK1

1

1

High-throughput

0.536

High

1310160

KIFA3
Kinesin-associated protein 3

1

15

High-throughput

0.536

High

1310182

PSD13
26S proteasome non-ATPase regulatory subunit 13

1

2

High-throughput

0.536

High

417561

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.515

High

298020

SPF27
Pre-mRNA-splicing factor SPF27

1

0

High-throughput

0.513

High

633740

PSB1
Proteasome subunit beta type-1

1

0

High-throughput

0.513

High

1089325

AIMP1
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1

1

0

High-throughput

0.513

High

1006525

SRPK2
SRSF protein kinase 2

1

15

High-throughput

0.501

High

996755

TBA1B
Tubulin alpha-1B chain

1

10

High-throughput

0.489

High

1310165

KXDL1
KxDL motif-containing protein 1

1

4

High-throughput

0.489

High

227608

SPOP
Speckle-type POZ protein

1

7

Small-scale

0.481

High

164002

NDC80
Kinetochore protein NDC80 homolog

1

17

High-throughput

0.479

High

164381

NRP1
Neuropilin-1

1

12

High-throughput

0.479

High

179958

BET1
BET1 homolog

1

5

High-throughput

0.479

High

218428

TGON2
Trans-Golgi network integral membrane protein 2

1

12

High-throughput

0.479

High

226114

STX6
Syntaxin-6

1

5

High-throughput

0.479

High

278887

PEX14
Peroxisomal membrane protein PEX14

1

2

High-throughput

0.479

High

291424

NU155
Nuclear pore complex protein Nup155

1

5

High-throughput

0.479

High

317654

ATG12
Ubiquitin-like protein ATG12

1

2

High-throughput

0.479

High

319887

UFL1
E3 UFM1-protein ligase 1

1

2

High-throughput

0.479

High

327345

ZFPL1
Zinc finger protein-like 1

1

2

High-throughput

0.479

High

342947

HERC2
E3 ubiquitin-protein ligase HERC2

1

9

High-throughput

0.479

High

404198

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

440139

LCK
Tyrosine-protein kinase Lck

1

9

High-throughput

0.479

High

459310

CATL1
Procathepsin L

1

4

High-throughput

0.479

High

459668

PROF1
Profilin-1

1

5

High-throughput

0.479

High

475624

K1C19
Keratin, type I cytoskeletal 19

1

15

High-throughput

0.479

High

488818

FURIN
Furin

1

2

High-throughput

0.479

High

560444

IFM1
Interferon-induced transmembrane protein 1

1

7

High-throughput

0.479

High

562197

LAMP2
Lysosome-associated membrane glycoprotein 2

1

7

High-throughput

0.479

High

604079

CXA1
Gap junction alpha-1 protein

1

8

High-throughput

0.479

High

693022

DPP4
Dipeptidyl peptidase 4

1

2

High-throughput

0.479

High

702010

TMOD1
Tropomodulin-1

1

5

High-throughput

0.479

High

774483

BASI
Basigin

1

7

High-throughput

0.479

High

778077

VGFR2
Vascular endothelial growth factor receptor 2

1

6

High-throughput

0.479

High

820683

CEAM6
Cell adhesion molecule CEACAM6

1

6

High-throughput

0.479

High

860829

RS10
Small ribosomal subunit protein eS10

1

6

High-throughput

0.479

High

878505

PAXI
Paxillin

1

10

High-throughput

0.479

High

931558

RD23A
UV excision repair protein RAD23 homolog A

1

10

Small-scale

0.479

High

936379

AFAD
Afadin

1

20

High-throughput

0.479

High

936800

NP1L1
Nucleosome assembly protein 1-like 1

1

3

High-throughput

0.479

High

970744

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

7

High-throughput

0.479

High

974947

TYB4
Thymosin beta-4

1

1

High-throughput

0.479

High

989042

AP2B1
AP-2 complex subunit beta

1

4

High-throughput

0.479

High

996233

EF1A1
Elongation factor 1-alpha 1

1

1

High-throughput

0.479

High

997021

TBA4A
Tubulin alpha-4A chain

1

9

High-throughput

0.479

High

998516

H31
Histone H3.1

1

8

High-throughput

0.479

High

1047922

TLE2
Transducin-like enhancer protein 2

1

14

High-throughput

0.479

High

1102590

MTA1
Metastasis-associated protein MTA1

1

9

High-throughput

0.479

High

1110647

DCTN2
Dynactin subunit 2

1

1

High-throughput

0.479

High

1110801

PKD2
Polycystin-2

1

10

High-throughput

0.479

High

1113624

CUL3
Cullin-3

1

15

High-throughput

0.479

High

1143401

PCM1
Pericentriolar material 1 protein

1

3

High-throughput

0.479

High

1158911

RBBP7
Histone-binding protein RBBP7

1

9

High-throughput

0.479

High

1227014

A16L1
Autophagy-related protein 16-1

1

16

High-throughput

0.479

High

1246872

RICTR
Rapamycin-insensitive companion of mTOR

1

9

High-throughput

0.479

High

1251923

LMTK1
Serine/threonine-protein kinase LMTK1

1

20

High-throughput

0.479

High

1310153

FBXW8
F-box/WD repeat-containing protein 8

1

11

High-throughput

0.479

High

1310161

PF21A
PHD finger protein 21A

1

20

High-throughput

0.479

High

1310162

RNF31
E3 ubiquitin-protein ligase RNF31

1

20

High-throughput

0.479

High

1310166

GORS1
Golgi reassembly-stacking protein 1

1

2

High-throughput

0.479

High

1310168

ACE2
Angiotensin-converting enzyme 2

1

9

High-throughput

0.479

High

1310171

TMT1A
Thiol S-methyltransferase TMT1A

1

2

High-throughput

0.479

High

1310174

SMC4
Structural maintenance of chromosomes protein 4

1

10

High-throughput

0.479

High

1310175

ELOV5
Very long chain fatty acid elongase 5

1

2

High-throughput

0.479

High

1310177

ANFY1
Rabankyrin-5

1

11

High-throughput

0.479

High

1310178

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

2

High-throughput

0.479

High

1310180

ANC2
Anaphase-promoting complex subunit 2

1

18

High-throughput

0.479

High

1310181

RCOR1
REST corepressor 1

1

9

High-throughput

0.479

High

1252886

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.458

High

1310172

SPC25
Kinetochore protein Spc25

1

0

High-throughput

0.458

High

1310164

CDC5L
Cell division cycle 5-like protein

1

5

High-throughput

0.457

High

1259327

TBA1A
Tubulin alpha-1A chain

1

10

High-throughput

0.445

High

1310158

ESR2
Estrogen receptor beta

1

20

High-throughput

0.445

High

139921

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

2

High-throughput

0.437

High

1031449

IFM3
Interferon-induced transmembrane protein 3

1

7

High-throughput

0.437

High

1208161

NKAPL
NKAP-like protein

1

1

High-throughput

0.437

High

1233327

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.437

High

1254535

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

1310152

CXD3
Gap junction delta-3 protein

1

8

High-throughput

0.437

High

1310169

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

2

High-throughput

0.437

High

1310176

SEP10
Septin-10

1

4

High-throughput

0.437

High

1310183

LAMP3
Lysosome-associated membrane glycoprotein 3

1

6

High-throughput

0.437

High

1167073

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

4

High-throughput

0.407

High

615188

PACA
Pituitary adenylate cyclase-activating polypeptide

3

0

High-throughput

0.347

High

1310173

HINT3
Adenosine 5'-monophosphoramidase HINT3

2

0

High-throughput

0.313

High

1310154

CBY2
Protein chibby homolog 2

1

0

High-throughput

0.279

Low

516850

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

0

High-throughput

0.232

Low

1310167

SC11C
Signal peptidase complex catalytic subunit SEC11C

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025