HitPredict

Interactor 1: GBG5 (P63218)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
Gene: GNG5

Interactor 2: PHLP (Q13371)
Phosducin-like protein (PHLP)
Gene: PDCL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 68 Hs			1 301
+	Hs
		1103671 GBG12_HUMAN (2-68): 5.43e-26: 92: 46.27		PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00
+	Hs
		948060 GBG2_HUMAN (2-68): 6.58e-26: 91.6: 48.53		PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00
+	Hs
		992427 GBG3_HUMAN (1-68): 1.31e-25: 90.9: 46.38		PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00
+	Hs
		893568 GBG10_HUMAN (1-68): 5.96e-25: 89.3: 52.94		PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00
+	Hs
		893554 GBG4_HUMAN (2-68): 1.65e-24: 88.2: 45.59		PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00
+	Hs
		1103672 GBG8_HUMAN (2-68): 1.14e-23: 85.8: 44.12		PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00
+	Hs
		117 A0A024R161_HUMAN (17-68): 1.63e-18: 75.1: 48.08		PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00
+	Hs
		964191 GBG11_HUMAN (9-67): 1.68e-18: 73.1: 32.20		PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00
+	Hs
		992412 GBG1_HUMAN (9-67): 1.94e-18: 72.7: 28.33		PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00
+	Dm
		792388 GBG1_DROME (4-68): 3.23e-19: 74.7: 39.39		PHLP1_DROME (1-277): 9.43e-89: 267: 44.41
+	Hs
		300246 GBG13_HUMAN (7-68): 9.99e-21: 78.5: 25.81		GLRX3_HUMAN (171-250): 2.54e-20: 91: 23.46