HitPredict

Interactor 1: TLE5 (Q08117)
TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) (TLE family member 5, transcriptional modulator)
Gene: TLE5

Interactor 2: FOXL1 (Q12952)
Forkhead box protein L1 (Forkhead-related protein FKHL11) (Forkhead-related transcription factor 7) (FREAC-7)
Gene: FOXL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 197 Hs			1 345
+	Hs
		980931 TLE4_HUMAN (2-191): 3.57e-112: 338: 68.59		FOXL1_HUMAN (1-345): 1.46e-108: 322: 100.00
+	Hs
		980596 TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50		FOXL1_HUMAN (1-345): 1.46e-108: 322: 100.00
+	Hs
		980742 TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50		FOXL1_HUMAN (1-345): 1.46e-108: 322: 100.00
+	Hs
		877703 TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50		FOXA1_HUMAN (5-320): 1.41e-80: 255: 30.27
+	Hs
		877704 TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50		FOXA1_HUMAN (5-320): 1.41e-80: 255: 30.27
+	Hs
		877602 TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50		FOXG1_HUMAN (48-224): 2.13e-52: 182: 40.68
+	Hs
		980669 TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50		FOXA2_HUMAN (7-320): 8.22e-53: 182: 29.13
+	Hs
		980951 TLE4_HUMAN (2-191): 3.57e-112: 338: 68.59		FOXB1_HUMAN (38-315): 6.26e-51: 173: 29.14
+	Hs
		980930 TLE4_HUMAN (2-191): 3.57e-112: 338: 68.59		FOXI1_HUMAN (6-234): 5.98e-50: 172: 35.02
+	Hs
		877990 TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50		FOXA3_HUMAN (47-146): 1.57e-50: 173: 63.00
+	Hs
		980641 TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50		FOXB1_HUMAN (38-315): 6.26e-51: 173: 29.14
+	Hs
		980595 TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50		FOXI1_HUMAN (6-234): 5.98e-50: 172: 35.02
+	Hs
		980740 TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50		FOXC1_HUMAN (9-280): 1.15e-53: 186: 35.86
+	Hs
		877992 TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50		FOXA3_HUMAN (47-146): 1.57e-50: 173: 63.00
+	Hs
		980855 TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50		FOXB1_HUMAN (38-315): 6.26e-51: 173: 29.14
+	Hs
		980741 TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50		FOXI1_HUMAN (6-234): 5.98e-50: 172: 35.02
+	Mm
		1141982 TLE1_MOUSE (2-197): 2.15e-101: 310: 63.00		FOXG1_MOUSE (5-224): 1.31e-50: 176: 33.64
+	Rn
		88552 D3ZCM7_RAT (2-197): 5.48e-99: 304: 63.00		FOXG1_RAT (5-224): 1.63e-50: 176: 33.64
+	Hs
		993407 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		FOXI1_HUMAN (6-234): 5.98e-50: 172: 35.02
+	Hs
		236577 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		FOXD2_HUMAN (44-137): 3.56e-48: 170: 63.83