HitPredict

Interactor 1: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Interactor 2: SKI8 (Q9GZS3)
Superkiller complex protein 8 (Ski8) (Meiotic recombination REC14 protein homolog) (WD repeat-containing protein 61) [Cleaved into: Superkiller complex protein 8, N-terminally processed (WD repeat-containing protein 61, N-terminally processed)]
Gene: SKIC8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 709 Hs			1 305
+	Hs
		996930 SSRP1_HUMAN (1-709): 0: 805: 100.00		NLE1_HUMAN (7-304): 9.15e-91: 279: 21.61
+	Hs
		996813 SSRP1_HUMAN (1-709): 0: 805: 100.00		FBXW7_HUMAN (91-303): 1.6e-63: 214: 24.30
+	Hs
		996824 SSRP1_HUMAN (1-709): 0: 805: 100.00		SNR40_HUMAN (2-216): 4.5e-59: 194: 22.42
+	Hs
		209427 SSRP1_HUMAN (1-709): 0: 805: 100.00		PLRG1_HUMAN (4-217): 2.47e-43: 156: 22.52
+	Hs
		903169 SSRP1_HUMAN (1-709): 0: 805: 100.00		WDR5_HUMAN (179-304): 4.63e-41: 147: 33.33
+	Hs
		197008 SSRP1_HUMAN (1-709): 0: 805: 100.00		PRP4_HUMAN (218-304): 3.86e-14: 74.2: 13.68
+	Hs
		1281404 HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20		FBXW7_HUMAN (91-303): 1.6e-63: 214: 24.30
+	Hs
		881823 SOX10_HUMAN (444-707): 4.49e-36: 143: 14.93		FBXW7_HUMAN (91-303): 1.6e-63: 214: 24.30
+	Hs
		818834 SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15		FBXW7_HUMAN (91-303): 1.6e-63: 214: 24.30
+	Hs
		1288324 HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20		SNR40_HUMAN (2-216): 4.5e-59: 194: 22.42
+	Hs
		869834 PMS1_HUMAN (400-704): 7.54e-34: 141: 16.23		SNR40_HUMAN (2-216): 4.5e-59: 194: 22.42
+	Hs
		903450 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		WDR5_HUMAN (179-304): 4.63e-41: 147: 33.33
+	Hs
		567741 UBF1_HUMAN (416-655): 2.71e-11: 69: 14.52		FBXW7_HUMAN (91-303): 1.6e-63: 214: 24.30
+	Ce
		1089274 SOX2_CAEEL (503-706): 2.71e-35: 137: 15.46		WDR51_CAEEL (179-304): 4.56e-38: 140: 34.13
+	Hs
		817868 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		WDR5_HUMAN (179-304): 4.63e-41: 147: 33.33
+	Hs
		643290 HMGB2_HUMAN (540-698): 5.17e-15: 76.3: 23.53		WDR5_HUMAN (179-304): 4.63e-41: 147: 33.33
+	Hs
		449632 HMGB1_HUMAN (543-634): 1e-14: 75.5: 34.04		WDR5_HUMAN (179-304): 4.63e-41: 147: 33.33
+	Hs
		196970 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		PRP4_HUMAN (218-304): 3.86e-14: 74.2: 13.68
+	Hs
		818610 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		WDR3_HUMAN (6-218): 4.82e-10: 62.4: 25.56
+	Hs
		817979 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		TBL3_HUMAN (151-265): 1.22e-09: 61.2: 28.93