Interactor 1: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Interactor 2: CITE2 (Q99967)
Cbp/p300-interacting transactivator 2 (MSG-related protein 1) (MRG-1) (P35srj)
Gene: CITED2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.975

The method score is based on:

Property Details
Experiments 26496610, 9887100, 12586840, 11744733, 15154850, 25956243, 22075993, 10593900, 12778114
Identification Methods affinity chromatography technology, two hybrid, pull down, protein complementation assay, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CITED~zf-TAZ
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0001666 - response to hypoxia
GO:0003682 - chromatin binding
GO:0003713 - transcription coactivator activity
and 10 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 2414
Hs

1 270
+ Hs
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024