HitPredict

Interactor 1: F8WI37 (F8WI37)
Histone-lysine N-methyltransferase 2C (EC 2.1.1.364)
Gene: Kmt2c

Interactor 2: H33 (P84244)
Histone H3.3
Gene: H3-3a

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	24368734
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Histone~PHD, Histone~SET
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 4904 Mm			1 136
+	Hs
		998565 KMT2C_HUMAN (1-4904): 0: 2819: 84.61		H31_HUMAN (1-136): 3.09e-60: 183: 96.32
+	Hs
		1017037 KMT2C_HUMAN (1-4904): 0: 2819: 84.61		H33_HUMAN (1-136): 1.13e-59: 182: 100.00
+	Hs
		1161950 KMT2C_HUMAN (1-4904): 0: 2819: 84.61		H31T_HUMAN (1-136): 2.59e-59: 181: 93.38
+	Hs
		1258883 KMT2C_HUMAN (1-4904): 0: 2819: 84.61		H32_HUMAN (1-136): 5.34e-59: 180: 97.06
+	Hs
		998694 NSD1_HUMAN (4313-4903): 1.43e-102: 374: 17.07		H31_HUMAN (1-136): 3.09e-60: 183: 96.32
+	Hs
		1017124 NSD1_HUMAN (4313-4903): 1.43e-102: 374: 17.07		H33_HUMAN (1-136): 1.13e-59: 182: 100.00
+	Hs
		1162005 NSD1_HUMAN (4313-4903): 1.43e-102: 374: 17.07		H31T_HUMAN (1-136): 2.59e-59: 181: 93.38
+	Hs
		883661 NSD1_HUMAN (4313-4903): 1.43e-102: 374: 17.07		CENPA_HUMAN (9-133): 2.43e-45: 146: 50.76
+	Hs
		998821 EHMT1_HUMAN (4430-4900): 3.18e-85: 311: 16.83		H31_HUMAN (1-136): 3.09e-60: 183: 96.32
+	Hs
		1017218 EHMT1_HUMAN (4430-4900): 3.18e-85: 311: 16.83		H33_HUMAN (1-136): 1.13e-59: 182: 100.00
+	Dm
		381707 SET1_DROME (4503-4904): 8.29e-85: 313: 23.80		H3_DROME (1-136): 5.34e-59: 180: 97.06
+	Hs
		1162047 EHMT1_HUMAN (4430-4900): 3.18e-85: 311: 16.83		H31T_HUMAN (1-136): 2.59e-59: 181: 93.38
+	Hs
		216410 SUV91_HUMAN (4572-4903): 2.18e-90: 304: 19.18		H31_HUMAN (1-136): 3.09e-60: 183: 96.32
+	Mm
		1017384 EHMT2_MOUSE (4443-4900): 4.53e-83: 304: 17.43		H33_MOUSE (1-136): 1.13e-59: 182: 100.00
+	Hs
		216415 SUV91_HUMAN (4572-4903): 2.18e-90: 304: 19.18		H33_HUMAN (1-136): 1.13e-59: 182: 100.00
+	Hs
		216473 SUV91_HUMAN (4572-4903): 2.18e-90: 304: 19.18		H32_HUMAN (1-136): 5.34e-59: 180: 97.06
+	Hs
		216457 SUV91_HUMAN (4572-4903): 2.18e-90: 304: 19.18		H37_HUMAN (1-136): 4.56e-57: 175: 94.12
+	Hs
		216462 SUV91_HUMAN (4572-4903): 2.18e-90: 304: 19.18		H3C_HUMAN (1-136): 2e-56: 173: 95.59
+	Sc
		805564 SET1_YEAST (4523-4904): 8.67e-85: 307: 25.45		H3_YEAST (1-136): 3.63e-54: 168: 90.44
+	Hs
		883692 EHMT1_HUMAN (4430-4900): 3.18e-85: 311: 16.83		CENPA_HUMAN (9-133): 2.43e-45: 146: 50.76